21823-89-2

Upstream product

• 6974-32-9 1-O-acetyl-2,3,5-tri-O-benzoyl-β-D-ribofuranose 
• 67525-66-0 1-O-acetyl-2,3,5-tri-O-benzoyl-β-D-ribofuranose 

Downstream Products

• 59221-04-4 tri-O-benzoyl-1-(5-chloro-3-oxo-3H-[1,2,4]thiadiazol-2-yl)-β-D-1-deoxy-ribofuranose 
• 126193-21-3 C₃₁H₃₀N₄O₁₀ 
• 71397-61-0 4-(2,3,5-tri-O-benzoyl-β-D-ribofuranosyl)semicarbazide 
• 80063-08-7 N-(2,2-diethoxyethyl)-N'-(2,3,5-tri-O-benzoyl-β-D-ribofuranosyl)urea 
• 80049-52-1 1-formyl-4-(2,3,5-tri-O-benzoyl-β-D-ribofuranosyl)semicarbazide 
• 189131-47-3 N-(acetylamidino)-N'-(2,3,5-tri-O-benzoyl-β-D-ribosyl)urea 
• 207116-65-2 C₃₀H₂₇ClN₄O₉ 
• 207116-63-0 C₃₆H₃₂N₄O₉ 
• 211695-85-1 N⁴-Methyl-2',3',5'-tri-O-benzoyl-β-D-5-azacytidine 
• 211695-92-0 C₃₀H₃₀N₄O₈ 
• 105330-92-5 2',3',5'-tri-O-benzoyl-6-benzyl-5-azacytidine 
• 211695-93-1 N⁴-Methyl-2',3',5'-tri-O-benzoyl-α-D-5-azacytidine 
• 27826-76-2 4-methylamino-1-β-D-ribofuranosyl-1H-[1,3,5]triazin-2-one 
• 27826-77-3 4-dimethylamino-1-β-D-ribofuranosyl-1H-[1,3,5]triazin-2-one 

Relevant academic research and scientific papers

SYNTHESIS; MOLECULAR CONFORMATION AND BIOLOGICAL ACTIVITY OF 6-AMINO-5-AZACYTIDINE

Reaction of N-ethoxycarbonylguanidine II with 2,3,5-tri-O-benzoyl-β-D-ribosyl isocyanate (II) afforded N-ethoxycarbonylamidinourea IV, which was cyclized by bis(trimethylsilyl)acetamide to the 6-ethoxy derivative VII.Ammono- and methanolysis of intermedia

Syntheses and Structure Assignments of Six Azolinone Ribonucleosides

N-Ribosidation of a series of azolinones was achieved via silylation and SnCl4 catalysis.N-Ribosidation of 4-imidazolin-2-one gave 1-β-D-ribofuranosyl-4-imidazolin-2-one; of 1,2,4-triazolin-3-one gave 2- and 4-β-D-ribofuranosyl-1,2,4-triazolin-3-one, and 2,4-di-β-D-ribofuranosyl-1,2,4-triazolin-3-one; and of 2-tetrazolin-5-one gave 1-β-D-ribofuranosyl-2-tetrazolin-5-one and 1,4-di-β-D-ribofuranosyl-2-tetrazolin-5-one.Structure assignments were based on NMR and mass spectra, microanalytical data, and interconversions.The triazolinone monoriboside isomer structures were differentiated by 13C NMR long-range coupling patterns, and the assignments were confirmed by X-ray crystallography.New syntheses were developed for several of the ribonucleosides by fashioning the azolinone rings from 2,3,5-tri-O-benzoylribofuranosyl isocyanate.