80049-42-9

Upstream product

• 6974-32-9 1-O-acetyl-2,3,5-tri-O-benzoyl-β-D-ribofuranose 
• 930-33-6 2,4-dihydro-1,2,4-triazol-3-one 
• 999-97-3 1,1,1,3,3,3-hexamethyl-disilazane 
• 80049-44-1 4-(2,3,5-Tri-O-benzoyl-β-D-ribofuranosyl)-1,2,4-triazol-3(2H)-one 
• 22860-91-9 2,3,5-tri-O-benzoyl-D-ribofuranosyl bromide 
• 21823-89-2 2,3,5-tri-O-benzoyl-β-D-ribosyl isocyanate 
• 29706-90-9 β-D-2,3,5-tri-O-benzoylribofuranosyl chloride 
• 71397-61-0 4-(2,3,5-tri-O-benzoyl-β-D-ribofuranosyl)semicarbazide 
• 80049-52-1 1-formyl-4-(2,3,5-tri-O-benzoyl-β-D-ribofuranosyl)semicarbazide 

Relevant academic research and scientific papers

PREPARATION OF RIBOSYL DERIVATIVES OF 1,2,4-TRIAZOL-3(2H)-ONE AND 5-METHYL-1,2,4-TRIAZOL-3(2H)-ONE

Reaction of the silylated triazolone I with 2,3,5-tri-O-benzoyl-D-ribofuranosyl bromide afforded a mixture of the 4-ribosyltriazolone IXa and 2,3-diribosyltriazolone Xa.Under the same conditions the silylated 5-methyltriazolone II gives the 4-ribosyl deri

Syntheses and Structure Assignments of Six Azolinone Ribonucleosides

N-Ribosidation of a series of azolinones was achieved via silylation and SnCl4 catalysis.N-Ribosidation of 4-imidazolin-2-one gave 1-β-D-ribofuranosyl-4-imidazolin-2-one; of 1,2,4-triazolin-3-one gave 2- and 4-β-D-ribofuranosyl-1,2,4-triazolin-3-one, and 2,4-di-β-D-ribofuranosyl-1,2,4-triazolin-3-one; and of 2-tetrazolin-5-one gave 1-β-D-ribofuranosyl-2-tetrazolin-5-one and 1,4-di-β-D-ribofuranosyl-2-tetrazolin-5-one.Structure assignments were based on NMR and mass spectra, microanalytical data, and interconversions.The triazolinone monoriboside isomer structures were differentiated by 13C NMR long-range coupling patterns, and the assignments were confirmed by X-ray crystallography.New syntheses were developed for several of the ribonucleosides by fashioning the azolinone rings from 2,3,5-tri-O-benzoylribofuranosyl isocyanate.