218903-35-6

Upstream product

• 475232-31-6 formic acid 5-isopropoxy-2-(3-isopropoxy-4-methoxy-phenylethynyl)-4-methoxy-phenyl ester 
• 215715-44-9 5-isopropoxy-2-[2'-(3''-isopropoxy-4''-methoxyphenyl)ethynyl]-4-methoxybenzaldehyde 
• 215715-43-8 β,β-dibromo-3-isopropoxy-4-methoxystyrene 
• 200941-15-7 2-iodo-5-isopropoxy-4-methoxybenzaldehyde 
• 34123-66-5 O-isopropylisovanillin 
• 215715-45-0 5-isopropoxy-2-[2'-(3''-isopropoxy-4''-methoxyphenyl)ethynyl]-4-methoxyphenol 

Downstream Products

• 218903-30-1 6-isopropoxy-2-(3'-isopropoxy-4'-methoxyphenyl)-5-methoxy-3-(3'',4'',5''-trimethoxyphenyl)benzofuran 

Relevant academic research and scientific papers

Synthesis, X-Ray Crystal Structure and Tubulin-Binding Properties of a Benzofuran Analogue of the Potent Cytotoxic Agent Combretastatin A4

The benzofuran (4), a ring-fused analogue of the potent antimitotic agent combretastatin A4 (1), has been prepared by a convergent route involving 5-endo-dig iodocyclization of o-hydroxytolan (5) as the key step. Compound (4), which has been characterized crystallographically as well as spectroscopically, is inactive as a tubulin-binding agent.