21906-17-2

Basic information

• Product Name: 3-phenylbutan-2-amine
• Synonyms: dl-erythro-2-Amino-3-phenylbutane
• CAS NO: 21906-17-2
• Molecular Formula: C₁₀H₁₅N
• Molecular Weight: 149.2328
• Mol File: 21906-17-2.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 216.5°C at 760 mmHg
• Flash Point: 90.6°C
• Density: 0.932g/cm³
• Vapor Pressure: 0.139mmHg at 25°C
• Refractive Index: 1.518
• PKA: 10.00±0.10(Predicted)
• CAS DataBase Reference: 3-phenylbutan-2-amine(CAS DataBase Reference)
• NIST Chemistry Reference: 3-phenylbutan-2-amine(21906-17-2)
• EPA Substance Registry System: 3-phenylbutan-2-amine(21906-17-2)

Safety Data

• Hazardous Substances Data: 21906-17-2(Hazardous Substances Data)

Upstream product

• 769-59-5 3-phenyl-butan-2-one 
• 77287-34-4 formamide 
• 39775-68-3 3-hydroxy-3-phenyl-butan-2-one oxime 
• 64-19-7 acetic acid 
• 767-99-7 2-phenylbut-2-ene 
• 1823-91-2 1-phenylethyl cyanide 
• 19731-91-0 (2RS,3SR)-2-methyl-3-phenylbutanoic acid 
• 10588-22-4 threo-3-phenyl-2-butyl p-toluenesulfonate 
• 42879-13-0 Ethyl 2-methyl-3-phenylbutanoate 
• 40960-66-5 rac-(2R,3R)-3-phenylbutan-2-ol 
• 108-86-1 bromobenzene 

Downstream Products

• 64969-62-6 (+/-)-erythro-3-methylamino-2-phenyl-butane 
• 33603-05-3 (1R,2R)-1-methyl-2-phenyl-propylamine 
• 121560-20-1 N-((1R,2R)-1-methyl-2-phenyl-propyl)-benzamide 
• 42253-99-6 ethyl (S)-2-phenylpropionate 
• 2510-99-8 ethyl (R)-2-phenylpropionate 
• 121560-20-1 N-((1S,2S)-1-methyl-2-phenyl-propyl)-benzamide 
• 98154-55-3 dimethyl-((1RS,2RS)-1-methyl-2-phenyl-propyl)-amine 
• 18010-67-8 nicotinic acid-(1-methyl-2-phenyl-propylamide) 
• 141463-71-0 2-Chloro-N-((1R,2S)-1-methyl-2-phenyl-propyl)-acetamide 
• 141463-72-1 2-Chloro-N-((1S,2S)-1-methyl-2-phenyl-propyl)-acetamide 

Relevant articles and documents

Direct Access to Primary Amines from Alkenes by Selective Metal-Free Hydroamination

Direct and selective synthesis of primary amines from easily available precursors is attractive yet challenging. Herein, we report the rapid synthesis of primary amines from alkenes via metal-free regioselective hydroamination at room temperature. Ammonium carbonate was used as ammonia surrogate for the first time, allowing for efficient conversion of terminal and internal alkenes into linear, α-branched, and α-tertiary primary amines under mild conditions. This method provides a straightforward and powerful approach to a wide spectrum of advanced, highly functionalized primary amines which are of particular interest in pharmaceutical chemistry and other areas.