2510-99-8Relevant articles and documents
Kwok et al.
, p. 1275 (1972)
Method for synthesizing P-bromomethyl isobenzopropionic acid
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Paragraph 0026-0028, (2021/10/27)
The invention provides a method for synthesizing p-bromomethyl isobenzopropionic acid, and relates to the technical field of organic synthesis. The synthesis method disclosed by the invention comprises the synthesis of isobenzoates. Vilsmeier Reagent preparation method comprises the following steps: synthesizing aldehyde isopropylparaben, synthesizing methyl isopropylbenzene, separating and purifying bromomethyl isobenzopropionic acid and, and the like. The final para-position selectivity of the method can reach 90 - 97%, and the three-waste yield is greatly reduced.
Photocatalytic acyl azolium-promoted alkoxycarbonylation of trifluoroborates
Scheidt, Karl A.,Zhu, Joshua L.
, (2021/06/28)
Despite recent advancements in the selective generation and coupling of organic radical species, the alkoxycarbonyl radical remains underexplored relative to other carbon-containing radical species. Drawing inspiration from new strategies for generating acyl radical equivalents utilizing dual N-heterocyclic carbene catalysis and photocatalysis, we have prepared dimethylimidazolium esters that can function as an alkoxycarbonyl radical surrogate under photocatalytic conditions. We demonstrate the synthetic utility of these azolium-based partners through the preparation of esters arising from the coupling of this radical surrogate with an oxidatively generated alkyl radical.