21960-27-0

Upstream product

• 60610-05-1 (2-methylpropyl)triphenylphosphonium iodide 
• 22884-29-3 isobutyltriphenylphosphonium bromide 
• 603-35-0 triphenylphosphine 

Downstream Products

• 105897-81-2 Trimethyl-[(1S,5S,6R)-6-((E)-3-methyl-but-1-enyl)-5-(tetrahydro-pyran-2-yloxymethyl)-cyclohex-2-enyloxy]-silane 
• 94202-77-4 ((Z)-(R)-1,5-Dimethyl-hex-2-enylselanyl)-benzene 
• 15325-56-1 (Z)-3-methyl-1-phenylbut-1-ene 
• 15325-61-8 (E)-(3-methylbut-1-en-1-yl)benzene 
• 19776-13-7 (+/-)-erythro-3-methyl-1-phenylbutane-1,2-diol 
• 113234-69-8 1-(2-methylsulfanylbenzoyl)-2-methylpropylidene(triphenyl)phosphorane 
• 159052-00-3 1-cinnamoyl-2-methylpropylidene(triphenyl)phosphorane 
• 113234-65-4 1-(2-methoxybenzoyl)-2-methylpropylidene(triphenyl)phosphorane 
• 167561-51-5 <1-(2-Methylcinnamoyl)-2-methylprop-1-ylidene>triphenylphosphorane 
• 167561-56-0 <1-(2,4,6-Trimethylcinnamoyl)-2-methylprop-1-ylidene>triphenylphosphorane 
• 157492-81-4 Ph₃PC(i-Pr)HgN(Si(CH₃)3)2 
• 71920-25-7 [(C₆H₅)3PCH(CH(CH₃)2)AuCH(CH(CH₃)2)P(C₆H₅)3]⁽¹⁺⁾*Cl^(1-) = [((C₆H₅)3PCH(CH(CH₃)2))2Au]Cl 
• 76426-20-5 chloro(triphenylphosphonium isobutylide)cadmium chloride 
• 84508-35-0 [(C₆H₅)3PCH(CH(CH₃)2)Pb(C₆H₅)3]⁽¹⁺⁾*Cl^(1-)=[(C₆H₅)3PCH(CH(CH₃)2)Pb(C₆H₅)3]Cl 

Relevant academic research and scientific papers

Synthetic and Spectroscopic Investigations Enabled by Modular Synthesis of Molecular Phosphaalkyne Precursors

A series of dibenzo-7-phosphanorbornadiene compounds, Ph3PC(R)PA (1-R; A = C14H10, anthracene; R = Me, Et, iPr, sBu), are reported to be capable of thermal fragmentation to generate alkyl-substituted phosphaalkynes (RC≡P) concomitant with triphenylphosphine and anthracene. Facile preparation of these molecular precursors proceeds by treatment of ClPA with the appropriate ylide Ph3P=CHR (2 equiv). For methyl, ethyl, and isopropyl substituents, the phosphaalkyne conversions are measured to be 56-73% in solution by quantitative 31P NMR spectroscopy. In the case of compound 1-Me, the kinetic profile of its spontaneous unimolecular fragmentation is investigated by an Eyring analysis. The resulting 1-phosphapropyne is directly detected by solution NMR spectroscopy and gas phase rotational microwave spectroscopy. The latter technique allows for the first time measurement of the phosphorus-31 nuclear spin-rotation coupling tensor. The nuclear spin-rotation coupling provides a link between rotational and NMR spectroscopies, and is contextualized in relation to the chemical shift anisotropy.

Tunable stereoselective alkene synthesis by treatment of activated imines with nonstabilized phosphonium ylides

A broad range of readily accessible N-sulfonyl imines undergo olefination reaction with nonstabilized phosphonium ylides under mild conditions to afford an array of both Z- and E-isomers of 1,2-disubstituted alkenes, allylic alcohols, and allylic amines in good yields and with greater than 991 stereoselectivity.

Gold catalysis: Synthesis of 3-acylindenes from 2-alkynylaryl epoxides

A series of 2-alkynylaryl epoxides were prepared by a sequence of Sonogashira coupling, Wittig olefination and epoxidation or a Darzens' glycid ester synthesis. The conversion of these substrates with gold(I) catalysts furnished 3-acylindenes and, in occa

FUSED HETEROCYCLIC COMPOUND

The present invention provides a compound represented by the formula: wherein R1ais a hydrogen atom, R2a is a C1-6 alkyl group substituted by a group represented by-NR6a-CO-(CH2) n-SO2

Cyclocondensation of oxalyl chloride with 1,2-glycols

Oxalyl chloride reacts with a wide range of acyclic 1,2-glycols 1 in the presence of triethylamine to produce 1,3-dioxolan-2-ones 3 together with 1,4-dioxane-2,3-diones 2. Ethylene glycol (1d), monosubstituted ethylene glycols 1e, j-l, and erythro-1,2-disubstituted ethylene glycols 1f, m, o provide the cyclic carbonates 3 as the minor products, while the threo-compounds 1g, i, n, p, q and pinacol (1h) afford 3 as the main products. The formation of 3 may be rationalized in terms of stereoelectronically controlled cleavage of the conjugate base 17- of the tetrahedral intermediates. The rate of the conformational change of 17- into 18- and the equilibrium constant between these conformers are proposed to be the major factors affecting the reaction pattern.

Untersuchungen im Wittig-System nach einem ordnenden Konzept auf der Basis alternativer Prinzipien

Our results show that the stereoselectivity of the Wittig-reaction can be controlled by the variation of substituents in accord with the ORDERING CONCEPT OF ALTERNATIV PRINCIPLES (individual pairs, known and unknown classes of alternatives).The "all-phenyl Wittig-system" having three phenyl groups on phosphorous two in ylid- and aldehyd-position was chosen as a standard for our investigations.Differentiation in ylid-position and compensation on phosphorous and aldehyd-position were observed by the comparison of "patterns".Consequently, most of the selectivity rules of Wittig-reactions can be explained by the differentiation through alternatives in the ylid-position.Inversion or conservation of the "patterns" of measured data points to the variation in structure of starting materials, reaction rates and selectivities.Amount-controls were also described in certain systems.