219670-51-6Relevant academic research and scientific papers
Substituent effects on the iodine-catalyzed thermal cyclization of 3,4-diphenylbuta-1,3-dienyl isocyanates: Mechanistic studies
Chuang, Ta-Hsien,Chang, Wei-Yu,Li, Chien-Fu,Wen, Yu-Chia,Tsai, Chia-Chen
, p. 9678 - 9686 (2012/01/05)
The thermal cyclization of 3,4-diphenylbuta-1,3-dienyl isocyanates 1, generated in situ from the corresponding azides, was investigated using iodine as a catalyst. Diphenylpyridinones 2, phenylnaphthalenes 3, and indenes 4 were produced via intramolecular ring closure. The nature of the substituents on the phenyl rings was found to be crucial to the distribution of cyclized products 2 - 4. The mechanism of the reaction is also discussed.
Discovery of Diarylacrylonitriles as a Novel Series of Small Molecule Sortase A Inhibitors
Oh, Ki-Bong,Kim, Soo-Hwan,Lee, Jaekwang,Cho, Won-Jea,Lee, Taeho,Kim, Sanghee
, p. 2418 - 2421 (2007/10/03)
On the basis of a hit from random screening, a novel class of small-molecule sortase A inhibitors was generated. The primary structure-activity relationship and the minimal structural requirements for potency were established through structural modifications and molecular modeling studies.
Rhodium-katalysierte Hydroformylierung innerer Alkine zu α,β-ungesaettigten Aldehyden
Johnson, John R.,Cuny, Gregory D.,Buchwald, Stephen L.
, p. 1877 - 1879 (2007/10/03)
Keywords: Alkine; Hydroformylierungen; Katalyse; Alkene; Rhodiumverbindungen
