219897-59-3Relevant academic research and scientific papers
Highly regioselective N-alkylation of nonracemic Betti base: A novel one-pot synthesis of chiral N-methyl-N-alkyl Betti bases
Dong, Yanmei,Sun, Jianwei,Wang, Xinyan,Xu, Xuenong,Cao, Liya,Hu, Yuefei
, p. 1667 - 1672 (2007/10/03)
A novel one-pot preparation of chiral N-methyl-N-alkyl Betti bases has been developed involving a highly regioselective N-alkylation of (S)-(+)-Betti base. The strategy involved formation-cleavage of the oxazine ring and N-methylation with BtCH2/sub
The Betti base: Absolute configuration and routes to a family of related chiral nonracemic bases
Cardellicchio, Cosimo,Ciccarella, Giuseppe,Naso, Francesco,Schingaro, Emanuela,Scordari, Fernando
, p. 3667 - 3675 (2007/10/03)
A detailed protocol for the resolution of the Betti base [i.e. 1-(α- aminobenzyl)-2-naphthol] was investigated and the absolute configuration of the two isomers was established by means of an X-ray diffractometric study. A series of optically active deriv
