219989-61-4Relevant academic research and scientific papers
Synthesis and comparative evaluation of two antiviral agents: β-L- Fd4C and β-D-Fd4C
Chen, Shu-Hui,Lin, Stanley,King, Ivan,Spinka, Tracy,Dutschman, Ginger E.,Gullen, Elizabeth A.,Cheng, Yung-Chi,Doyle, Terrence W.
, p. 3245 - 3250 (1998)
The synthesis of β-D-Fd4C was achieved in a stereoselective fashion from D-xylose. The antiviral activity and cytotoxicity of β-D-Fd4C was compared with that of β-L-Fd4C and 3TC (Lamivudine). Of the three agents compared, β-L-Fd4C was found to be the most potent antiviral agent.
