220034-56-0

Basic information

• Product Name: Dibenzyl-{2-[4,7-dimethoxy-1-(toluene-4-sulfonyl)-1H-indol-3-yl]-ethyl}-amine
• Synonyms: Dibenzyl-{2-[4,7-dimethoxy-1-(toluene-4-sulfonyl)-1H-indol-3-yl]-ethyl}-amine
• CAS NO: 220034-56-0
• Molecular Weight: 554.71
• Mol File: 220034-56-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Dibenzyl-{2-[4,7-dimethoxy-1-(toluene-4-sulfonyl)-1H-indol-3-yl]-ethyl}-amine(CAS DataBase Reference)
• NIST Chemistry Reference: Dibenzyl-{2-[4,7-dimethoxy-1-(toluene-4-sulfonyl)-1H-indol-3-yl]-ethyl}-amine(220034-56-0)
• EPA Substance Registry System: Dibenzyl-{2-[4,7-dimethoxy-1-(toluene-4-sulfonyl)-1H-indol-3-yl]-ethyl}-amine(220034-56-0)

Safety Data

• Hazardous Substances Data: 220034-56-0(Hazardous Substances Data)

Upstream product

• 103-49-1 dibenzylamine 
• 96005-26-4 N,N-dibenzyl-2-(4,7-dimethoxy-indol-3-yl)-2-oxo-acetamide 
• 805953-02-0 N,N-dibenzyl-4,7-dimethoxytryptamine 
• 98-59-9 p-toluenesulfonyl chloride 
• 23876-39-3 4,7-dimethoxylindole 

Downstream Products

• 220034-71-9 tert-butyl (2-{4,7-dimethoxy-1-[(4-methylphenyl)sulfonyl]-1H-indol-3-yl}ethyl)carbamate 
• 220034-57-1 tert-butyl (2-{1-[(4-methylphenyl)sulfonyl]-4,7-dioxo-4,7-dihydro-1H-indol-3-yl}ethyl)carbamate 
• 1026325-96-1 2-[4,7-dimethoxy-1-(toluene-4-sulfonyl)-1H-indol-3-yl]ethylamine 

Relevant articles and documents

A biomimetic approach to the discorhabdin alkaloids: Total syntheses of discorhabdins C and E and dethiadiscorhabdin D

The characteristic spirodienone structure of the discorhabdin alkaloids is readily formed by reaction of the tyramine-substituted indoloquinonimines 26, 35, and 36 with cupric chloride, triethylamine, and oxygen. This cyclization provides a possibly biomimetic route to discorhabdins C and E (41 and 42). The unbrominated spirodienone 40 reacts with hydrogen over Pd/C to give enone 46. Bromination at the α position gives a mixture of bromoenones that undergo smooth conversion to dethiadiscorhabdin D (4) upon treatment with basic alumina.