96005-26-4

Upstream product

• 79-37-8 oxalyl dichloride 
• 23876-39-3 4,7-dimethoxylindole 
• 103-49-1 dibenzylamine 

Downstream Products

• 220034-56-0 Dibenzyl-{2-[4,7-dimethoxy-1-(toluene-4-sulfonyl)-1H-indol-3-yl]-ethyl}-amine 
• 220034-71-9 tert-butyl (2-{4,7-dimethoxy-1-[(4-methylphenyl)sulfonyl]-1H-indol-3-yl}ethyl)carbamate 
• 220034-57-1 tert-butyl (2-{1-[(4-methylphenyl)sulfonyl]-4,7-dioxo-4,7-dihydro-1H-indol-3-yl}ethyl)carbamate 
• 1026325-96-1 2-[4,7-dimethoxy-1-(toluene-4-sulfonyl)-1H-indol-3-yl]ethylamine 
• 805953-02-0 N,N-dibenzyl-4,7-dimethoxytryptamine 

Relevant academic research and scientific papers

A biomimetic approach to the discorhabdin alkaloids: Total syntheses of discorhabdins C and E and dethiadiscorhabdin D

The characteristic spirodienone structure of the discorhabdin alkaloids is readily formed by reaction of the tyramine-substituted indoloquinonimines 26, 35, and 36 with cupric chloride, triethylamine, and oxygen. This cyclization provides a possibly biomimetic route to discorhabdins C and E (41 and 42). The unbrominated spirodienone 40 reacts with hydrogen over Pd/C to give enone 46. Bromination at the α position gives a mixture of bromoenones that undergo smooth conversion to dethiadiscorhabdin D (4) upon treatment with basic alumina.