220034-71-9

Upstream product

• 24424-99-5 di-tert-butyl dicarbonate 
• 1026325-96-1 2-[4,7-dimethoxy-1-(toluene-4-sulfonyl)-1H-indol-3-yl]ethylamine 
• 23876-39-3 4,7-dimethoxylindole 
• 220034-56-0 Dibenzyl-{2-[4,7-dimethoxy-1-(toluene-4-sulfonyl)-1H-indol-3-yl]-ethyl}-amine 
• 98-59-9 p-toluenesulfonyl chloride 
• 96005-26-4 N,N-dibenzyl-2-(4,7-dimethoxy-indol-3-yl)-2-oxo-acetamide 
• 805953-02-0 N,N-dibenzyl-4,7-dimethoxytryptamine 
• 170489-17-5 4,7-dimethoxy-1H-indole-3-carboxaldehyde 
• 91557-43-6 2-(4,7-dimethoxy-1H-indol-3-yl)ethylamine 
• 92033-00-6 1-(4,7-dimethoxy-1H-indol-3-yl)-N,N-dimethylmethanamine 
• 15109-37-2 (4,7-dimethoxy-1H-indol-3-yl)acetonitrile 
• 892111-68-1 4,7-dimethoxy-3-(2-nitro-vinyl)-1-(toluene-4-sulfonyl)-1H-indole 
• 349491-08-3 4,7-dimethoxy-3-(2-nitro-vinyl)-1H-indole 

Downstream Products

• 220034-57-1 tert-butyl (2-{1-[(4-methylphenyl)sulfonyl]-4,7-dioxo-4,7-dihydro-1H-indol-3-yl}ethyl)carbamate 
• 892113-31-4 7-methyl-5-(toluene-4-sulfonyl)-2,3,5,7-tetrahydro-1,5,7,8-tetraaza-cyclopenta[e]acenaphthylen-6-one 
• 892113-63-2 9-methyl-5-[(4-methylphenyl)sulfonyl]-2,3,5,9-tetrahydro-6H-pyrazolo[4,3-h]pyrrolo[4,3,2-de]quinolin-6-one 
• 892113-57-4 5-(toluene-4-sulfonyl)-2,3,5,9-tetrahydro-1,5,8,9-tetraaza-cyclopenta[e]acenaphthylen-6-one 
• 892113-24-5 5-(toluene-4-sulfonyl)-2,3,5,7-tetrahydro-1,5,7,8-tetraaza-cyclopenta[e]acenaphthylen-6-one 
• 892113-75-6 7-(4-hydroxy-phenyl)-5-(toluene-4-sulfonyl)-2,3,5,9-tetrahydro-1,5,8,9-tetraaza-cyclopenta[e]acenaphthylen-6-one 
• 892113-43-8 9-(4-hydroxy-phenyl)-5-(toluene-4-sulfonyl)-2,3,5,7-tetrahydro-1,5,7,8-tetraaza-cyclopenta[e]acenaphthylen-6-one 
• 892113-50-7 9-(3-hydroxy-1-methyl-2-oxo-2,3-dihydro-1H-indol-3-yl)-5-[(4-methylphenyl)sulfonyl]-2,3,5,7-tetrahydro-6H-pyrazolo[3,4-h]pyrrolo[4,3,2-de]quinolin-6-one 
• 892113-84-7 7-(3-hydroxy-1-methyl-2-oxo-2,3-dihydro-1H-indol-3-yl)-5-(toluene-4-sulfonyl)-2,3,5,9-tetrahydro-1,5,8,9-tetraaza-cyclopenta[e]acenaphthylen-6-one 
• 892113-17-6 tert-butyl (2-{1-(3-hydroxy-1-methyl-2-oxo-2,3-dihydro-1H-indol-3-yl)-5-[(4-methylphenyl)sulfonyl]-4,8-dioxo-1,4,5,8-tetrahydro-pyrrolo[2,3-f]indazol-7-yl}ethyl)carbamate 
• 892112-74-2 tert-butyl (2-{1-(3-hydroxy-1-methyl-2-oxo-2,3-dihydro-1H-indol-3-yl)-7-[(4-methylphenyl)sulfonyl]-4,8-dioxo-1,4,7,8-tetrahydro-pyrrolo[3,2-f]indazol-5-yl}ethyl)carbamate 

Relevant academic research and scientific papers

Synthesis and antitumor characterization of pyrazolic analogues of the marine pyrroloquinoline alkaloids: Wakayin and tsitsikammamines

A series of aza analogues of the marine alkaloids wakayin and tsitsikammamines A and B have been synthesized. The strategy used was based on [3 + 2] cycloaddition reactions involving 3-ethylamine-indole-4,7-dione and different diazo reagents. All the comp

A biomimetic approach to the discorhabdin alkaloids: Total syntheses of discorhabdins C and E and dethiadiscorhabdin D

The characteristic spirodienone structure of the discorhabdin alkaloids is readily formed by reaction of the tyramine-substituted indoloquinonimines 26, 35, and 36 with cupric chloride, triethylamine, and oxygen. This cyclization provides a possibly biomimetic route to discorhabdins C and E (41 and 42). The unbrominated spirodienone 40 reacts with hydrogen over Pd/C to give enone 46. Bromination at the α position gives a mixture of bromoenones that undergo smooth conversion to dethiadiscorhabdin D (4) upon treatment with basic alumina.