220061-73-4Relevant academic research and scientific papers
SILOXY-WITTIG REARRANGEMENT: A NEW METHOD FOR DIASTEREOSELECTIVE PREPARATIONS OF 1,2-DIOL SYSTEMS
Nakai, Ei-ichi,Nakai, Takeshi
, p. 5409 - 5412 (1988)
A novel Wittig variant, termed "siloxy-Wittig rearrangement", has been developed which provides the half-silylated 1,2-diol systems with a high anti-diastereoselectivity.The unusual anti-selectivity is discussed on mechanistic grounds.
A mild and efficient method for tetrahydropyranylation/depyranylation of alcohols and phenols under neutral conditions
Reddy,Reddy,Bhanumathi,Rao
, p. 4323 - 4328 (2007/10/03)
Alcohols and phenols are tetrahydropyranylated rapidly in high yields in the presence of lithium bromide and dichloromethane at room temperature. Deprotection of these THP ethers can also be effected readily by mere change of the solvent to methanol and refluxing with excess lithium bromide. Due to neutral reaction conditions employed, the method is also compatible with compounds having acid sensitive functional groups.
Iodine-Catalyzed Mild and Efficient Tetrahydropyranylation/Depyranylation of Alcohols
Kumar, H. M. Sampath,Reddy, B. V. Subba,Reddy, E. Jagan,Yadav, J. S.
, p. 857 - 858 (2007/10/03)
Alcohols and phenols are tetrahydropyranylated rapidly in high yields in the presence of catalytic amount of iodine at room temperature. Depyranylation is effected readily by refluxing with iodine in methanol for few hours.
