220189-07-1Relevant articles and documents
Synthesis of Ibuprofen Hybrid Conjugates as Anti-Inflammatory and Analgesic Agents
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Paragraph 0186; 0188; 0191-0192, (2021/11/26)
Disclosed herein as ibuprofen hybrid conjugates and methods of their use to reduce inflammation, pain, and fever. The ibuprofen conjugates have potent anti-inflammatory and analgesic properties with low potential for ulcerogenic activity. An exemplary com
Synthesis and preliminary biological evaluation of capsaicin derivativesas potential analgesic drugs
Qian, Hai,Fu, Zhixian,Huang, Wenlong,Zhang, Huibin,Zhou, Jinpei,Ge, Liang,Lin, Rui,Lin, Haiyan,Hu, Xiaowen
experimental part, p. 205 - 210 (2011/09/14)
A series of capsaicin derivatives were designed and synthesized, including 10 compounds which are the combination of capsaicin and dihydro capsaicin with ibuprofen through bridge chain. Preliminary biological tests suggested that some compounds had both a
