220438-13-1Relevant academic research and scientific papers
B(OMe)3 as a nonacidic iminium ion generator in Mannich- and Ugi-type reactions
Tanaka, Yusuke,Hidaka, Kousuke,Hasui, Tomoaki,Suginome, Michinori
supporting information; experimental part, p. 1148 - 1151 (2009/07/11)
Mannich-type reactions of aldehydes with secondary amines and a ketene silyl acetal were promoted by trimethoxyborane in DMSO to afford the corresponding β-amino esters in good yields. B(OMe)3 also promoted Ugi-type reactions of aldehydes with
Novel isomerization reaction of N,N-dimethyl-α-(methoxycarbonyl)-4- substituted-benzylammonium N-methylides
Zhang, Chen,Ito, Hiroto,Maeda, Yasuhiro,Shirai, Naohiro,Ikeda, Shin-Ichi,Sato, Yoshiro
, p. 581 - 586 (2007/10/03)
Fluoride ion-induced desilylation of N,N-dimethyl-N- [(trimethylsilyl)methyl]-α-(methoxycarbonyl)4-substituted benzylammonium salts (7) gave two Stevens rearrangement products: methyl 3-(dimethylamino)- 2-(4-substituted phenyl)propionates (13) from N-methylides 8, and methyl 3- (dimethylamino)-3-(4-substituted phenyl)propionates (15) from N-benzylides 10. Additional Stevens rearrangement products, methyl 2-(dimethylamino)-3- (4-substituted phenyl)propionates (16), were competitively formed from ylides 12 when the cesium fluoride used was not predried. The mechanism of the isomerization from methylides 8, which was initially generated, to 10 and 12 is discussed.
The Chemistry and Occurrence of Taxane Derivatives. X. The Photochemistry of Taxine B.
Appendino, Giovanni,Cravotto, Giancarlo,Gariboldi, Pierluigi,Gabetta, Bruno,Bombardelli, Ezio
, p. 1 - 4 (2007/10/02)
The photodegradation of taxine B, 1, gave, besides the expected cyclization of 13-oxo-Δ4(20),11-taxadiene system, reductive cleavage of the nitrogen-carbon bond.The same behaviour was found in other Winterstein acid esters, which were photolytically converted to their corresponding β-phenylpropionates.
