22072-45-3Relevant academic research and scientific papers
Production method of 5-phthalancarbonitrile compound, intermediate therefor and production method of the intermediate
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, (2008/06/13)
The present invention provides a production method of a 5-phthalancarbonitrile compound, which comprises the use of a novel compound of the formula [I] wherein X is chlorine atom, bromine atom or iodine atom, as a key intermediate; intermediate; and the process of preparing intermediates.
Synthetic Study of Selective Benzylic Oxidation
Wang, Wuyi,Li, Tiechao,Attardo, Giorgio
, p. 6598 - 6602 (2007/10/03)
Oxidation of bisbenzyl ethers was studied using 2,3-dichloro-5,6-dicyanobenzoquinone (DDQ). Compared to other benzylic oxidations such as Kornblum type reaction of benzyl bromides or MnO2 oxidation of benzyl alcohols, DDQ oxidation offered advantages of being mild and highly selective to provide monoaldehyde products. We have explored factors which influence the course of the reaction and exemplified the synthetic value of the approach by preparing a number of aromatic intermediates (7-8, 15-25).
A convenient synthesis of methyl- and isopropyl-benzyl ethers using silver(II) oxide as reagent
Ortiz,Walls,Yuste,Barrios,Sanchez-Obregon,Pinelo
, p. 749 - 756 (2007/10/02)
Substituted bromomethyl- and chloromethylbenzenes and bis(bromomethyl) benzenes were directly converted, in high yields, to the corresponding methyl- and isopropyl-benzyl ethers by treatment with silver(II) oxide in methanol or isopropanol.
Microbial Stereodifferentiating Reduction of (+/-)4-Methyl- and (+/-)-6-Methyl-1-oxometacyclophanes and Revision of the Absolute Configuration of 4-Substituted Metacyclophanes
Nakazaki, Masao,Hirose, Yoshiki,Shimizu, Toru,Suzuki, Takaaki,Ishii, Akira,Makimura, Masaru
, p. 1428 - 1435 (2007/10/02)
Partial oxidative hydrolysis of 4-bromo-1,1,10,10-bis(trimethylenedithio)metacyclophane (7) yielded the bromo ketones 8 and 9 which were respectively converted into (+/-)-4-methyl- (3) and (+/-)-6-methyl-1-oxometacyclophanes (4).The unambiguous synthesis of (+/-)-3 from 2,5-dimethylbenzoic acid (18) assigned their structures.Incubation of (+/-)-3 with Rhodotorula rubra gave a mixture of (-)-ketone 3, (-) axial alcohol 38, and (-) equatorial alcohol 39.The observed (-) Cotton effect indicated the pS configuration of (-)-3, and transformation of (-)-3 into (+)-4-methylmetacyclophane (5) permitted the assignment of the pR configuration to (+)-5, opposite to Schloegl's proposal.This conclusion was further supported by the parallel sequence of the steps starting from (+/-)-6-methyl ketone.
Benz (c) fluoran compounds and recording sheet containing them
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, (2008/06/13)
Novel benz[c]fluoran compounds such as 2-phenylamino-8-diethylamino-benz[c]fluoran, 2-(2',4',6'-trimethylphenylamino)-8-diethylamino-benz[c]fluoran and N-[8-diethylaminobenz[c]fluoran-2-yl]-N-[6-diethylaminofluoran-2-yl]amine, which are useful as a coloring material for record material systems such as pressure-sensitive copying paper or heat-sensitive copying paper, wherein colored images formed by an electron-donoracceptor color-forming reaction between coloring material and acidic material.
