220847-34-7

Basic information

• Product Name: 4-nitro-N-[(2,6-dimethylphenyl)carbonyl]-L-phenylalanine methyl ester
• Synonyms: 4-nitro-N-[(2,6-dimethylphenyl)carbonyl]-L-phenylalanine methyl ester
• CAS NO: 220847-34-7
• Molecular Weight: 356.378
• Mol File: 220847-34-7.mol

Chemical Properties

• CAS DataBase Reference: 4-nitro-N-[(2,6-dimethylphenyl)carbonyl]-L-phenylalanine methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 4-nitro-N-[(2,6-dimethylphenyl)carbonyl]-L-phenylalanine methyl ester(220847-34-7)
• EPA Substance Registry System: 4-nitro-N-[(2,6-dimethylphenyl)carbonyl]-L-phenylalanine methyl ester(220847-34-7)

Safety Data

• Hazardous Substances Data: 220847-34-7(Hazardous Substances Data)

Upstream product

• 85317-52-8 methyl 2-amino-3-(4-nitrophenyl)propionate 
• 21900-37-8 2,6-dimethylbenzoyl chloride 
• 949-99-5 4-nitro-3-phenyl-L-alanine 
• 632-46-2 2,6-dimethylbenzoic acid 
• 81677-60-3 (L)-p-Nitrophenylalanine methyl ester 

Downstream Products

• 220847-35-8 (S)-3-(4-Amino-phenyl)-2-(2,6-dimethyl-benzoylamino)-propionic acid methyl ester 

Relevant articles and documents

Focused library approach for identification of new N-acylphenylalanines as VCAM/VLA-4 antagonists.

A structure-based focused library approach was employed in an effort to identify more lipophilic replacements for the N-benzylpyroglutamyl group of the VCAM/VLA-4 antagonist 2. This effort led to the discovery of two new classes of potent antagonists char

N-aroylphenylalanine derivative VCAM-1 inhibitors

Compounds of the formula: are disclosed which have activity as inhibitors of binding between VCAM-1 and cells expressing VLA-4. Such compounds are useful for treating diseases whose symptoms and/or damage are related to the binding of VCAM-1 to cells expr