22106-39-4

Usage

Uses

Used in Pharmaceutical Synthesis:
3-Methoxy-4-nitroacetophenone is utilized as a key intermediate in the synthesis of various pharmaceuticals. Its unique structure allows for the creation of a wide range of complex molecules, contributing to the development of new drugs with diverse therapeutic applications.
Used in Agrochemical Production:
In the agrochemical industry, 3-Methoxy-4-nitroacetophenone serves as a vital component in the production of pesticides and other crop protection agents. Its incorporation into these products enhances their effectiveness in controlling pests and diseases, thereby improving agricultural yields.
Used in Antibacterial Agents:
Leveraging its inherent antibacterial properties, 3-Methoxy-4-nitroacetophenone is employed as an active ingredient in the development of antibacterial agents. These agents are designed to combat bacterial infections, offering a valuable solution in the ongoing battle against antibiotic resistance.
Used in Anti-inflammatory Medications:
Capitalizing on its anti-inflammatory characteristics, 3-Methoxy-4-nitroacetophenone is used in the formulation of anti-inflammatory drugs. These medications aim to alleviate inflammation and associated pain, providing relief to individuals suffering from various inflammatory conditions.

InChI:InChI=1/C9H9NO4/c1-6(11)7-3-4-8(10(12)13)9(5-7)14-2/h3-5H,1-2H3

Upstream product

• 186581-53-3 diazomethane 
• 89942-63-2 1-(5-hydroxy-4-nitrophenyl)ethanone 
• 67579-92-4 3-methoxy-4-nitrobenzoic acid chloride 
• 105-53-3 diethyl malonate 
• 108-59-8 malonic acid dimethyl ester 
• 91-23-6 2-Nitroanisole 
• 38512-82-2 3-methoxy-4-nitrotoluene 
• 5081-36-7 3-methoxy-4-nitrobenzoic acid 

Downstream Products

• 607713-40-6 2-amino-4-(3-methoxy-4-nitrophenyl)-3-thiophenecarbonitrile 
• 607713-42-8 5-(4-amino-3-methoxyphenyl)thieno[2,3-d]pyrimidin-4-amine 
• 93023-15-5 <4-Nitro-3-methoxy-phenacyl>-malonsaeurediaethylester 
• 1365620-93-4 (E)-[1-(1,3-dihydro-1-hydroxy-2,1-benzoxaborol-6-yl)-3-(3-methoxy-4-nitrophenyl)]propenone 
• 22106-40-7 1-(4-amino-3-methoxyphenyl)ethan-1-one 
• 5081-36-7 3-methoxy-4-nitrobenzoic acid 
• 1197180-35-0 C₁₀H₉N₃O₃ 

Relevant academic research and scientific papers

Reactions of 1-(benzotriazol-1-yl)-1-phenoxyalkane and (benzotriazol-1- yl)ethoxyphenylmethane anions with nitroarenes: A new approach to alkyl and aryl p-nitroaryl ketones

p-Nitroaryl alkyl ketones and p-nitroaryl aryl ketones are prepared regioselectively by reactions of non-functionalized nitroarenes and benzotriazole stabilized carbanions.

Diphenyl-aminopyrimidine compound for inhibiting kinase activity

The invention relates to a diphenyl-aminopyrimidine compound with an inhibiting function on protein tyrosine kinase, a pharmaceutical composition containing the diphenyl-aminopyrimidine compound, andpreparation and application of the diphenyl-aminopyrimidine compound, in particular to a compound shown as the formula (I) and pharmaceutically acceptable salt or crystal forms or prodrugs or metabolin or aquo-complex or solvate or isotope derivatives thereof, wherein R1, R2, R5, R6, R7, R8 and W are defined as the description. The compound can be used for treating ALK-mediated cancer related symptoms, such as non-small cell lung cancer or breast cancer or neural tumors or esophagus cancer or soft tissue cancer or lymphoma or leukemia. The formula is shown in the specification.

Heterocyclic Compounds and Methods of Use

This disclosure provides compounds and methods of using those compounds to treat liver fibrosis, including liver fibrosis which is a precursor to, is concurrent with, is associated with, or is secondary to nonalcoholic steatohepatitis (NASH); elevated cholesterol levels, and insulin resistance.

HETEROCYCLIC COMPOUNDS AND METHODS OF USE

This disclosure provides compounds and methods of using those compounds to treat metabolic disorders and hyperproliferative disorders, including administration of the compounds in conjunction with hormone receptor antagonists. Compounds of the invention may also find use in treating cancer. Presented herein are novel compounds bearing a perhaloalkylsulfonamide moiety. Such compounds, in addition to being highly effective SREBP inhibitors, are also unexpectedly highly bioavailable in vivo. Heteroaromatic compounds bearing sulfonamide groups are prone to several ionic states, based on the inherent pKa values.

HETEROCYCLIC COMPOUNDS AND METHODS OF USE

This disclosure provides compounds and methods of using those compounds to treat metabolic disorders and hyperproliferative disorders, including administration of the compounds in conjunction with hormone receptor antagonists.

PYRIMIDINYL-PYRAZOLE INHIBITORS OF AURORA KINASES

The present invention provides a compound represented by Formula (I): or a pharmaceutically acceptable salt thereof, or a solvate thereof, or a combination thereof, wherein the substituents are as defined herein. The present invention also relates to a co

Thienopyrimidine ureas as novel and potent multitargeted receptor tyrosine kinase inhibitors

A series of novel thienopyrimidine-based receptor tyrosine kinase inhibitors has been discovered. Investigation of structure-activity relationships at the 5- and 6-positions of the thienopyrimidine nucleus led to a series of N,N′-diaryl ureas that potentl

Thiopyrimidine and isothiazolopyrimidine kinase inhibitors

Compounds having the formula are useful for inhibiting protein tyrosine kinases. The present invention also discloses methods of making the compounds, compositions containing the compounds, and methods of treatment using the compounds.

Thiopyrimidine and isothiazolopyrimidine kinase inhibitors

Compounds having the formula are useful for inhibiting protein tyrosine kinases. The present invention also discloses methods of making the compounds, compositions containing the compounds, and methods of treatment using the compounds.

13C NMR Spectra of Substituted o-Nitroanisoles and n-Butyl o-Nitrophenyl Ethers

13C NMR analyses of substituted o-nitroanisoles and n-butyl o-nitrophenyl ethers are reported. Key Words: 13C NMR - o-Nitroanisoles - n-Butyl o-nitrophenyl ethers