38512-82-2

Basic information

• Product Name: 5-METHYL-2-NITROANISOLE
• Synonyms: 2-Methoxy-4-methylnitrobenzene;1-Nitro-2-methoxy-4-methylbenzene;3-Methyl-6-nitroanisole;Benzene,2-Methoxy-4-Methyl-1-nitro-;5-Methyl-2-nitroanisole 99%;2-Methoxy-4-methylnitrobenzene98%;NSC 124451;2-Nitro-5-methylanisole
• CAS NO: 38512-82-2
• Molecular Formula: C₈H₉NO₃
• Molecular Weight: 167.16
• EINECS: 253-975-1
• Product Categories: Aromatic Hydrocarbons (substituted) & Derivatives;Alpha sort;H-MAlphabetic;M;META - METH;Pesticides&Metabolites;Nitro Compounds;Nitrogen Compounds;Organic Building Blocks;blocks;NitroCompounds
• Mol File: 38512-82-2.mol
• Article Data: 14

Chemical Properties

• Melting Point: 58-60 °C(lit.)
• Boiling Point: 292 °C at 760 mmHg
• Flash Point: 142.9 °C
• Appearance: /
• Density: 1.18 g/cm³
• Vapor Pressure: 0.0033mmHg at 25°C
• Refractive Index: 1.538
• Storage Temp.: Sealed in dry,Room Temperature
• BRN: 2092369
• CAS DataBase Reference: 5-METHYL-2-NITROANISOLE(CAS DataBase Reference)
• NIST Chemistry Reference: 5-METHYL-2-NITROANISOLE(38512-82-2)
• EPA Substance Registry System: 5-METHYL-2-NITROANISOLE(38512-82-2)

Safety Data

• Hazard Codes: Xn,Xi
• Statements: 22-36/37/38
• Safety Statements: 26-36
• WGK Germany: 3
• Hazardous Substances Data: 38512-82-2(Hazardous Substances Data)

Usage

Uses

5-Methyl-2-nitroanisole may be used in chemical synthesis.

InChI:InChI=1/C8H9NO3/c1-6-3-4-7(9(10)11)8(5-6)12-2/h3-5H,1-2H3

Upstream product

• 186581-53-3 diazomethane 
• 700-38-9 2-nitro-5-methylphenol 
• 610-39-9 3,4-Dinitrotoluene 
• 124-41-4 sodium methylate 
• 77-78-1 dimethyl sulfate 
• 74-88-4 methyl iodide 
• 3465-63-2 4-Hydroxy-2-methoxy-6-methylbenzoesaeure-methylester 
• 93796-63-5 1-Bromo-3-methoxy-5-methyl-2-nitro-benzene 
• 509-14-8 tetranitromethane 
• 100-84-5 1-methoxy-3-methyl-benzene 
• 67-56-1 methanol 
• 52488-29-6 2-iodo-4-methyl-1-nitrobenzene 
• 108-39-4 3-methyl-phenol 
• 352-70-5 m-Fluorotoluene 

Downstream Products

• 65081-42-7 3-(N-methylamino)-4-nitrotoluene 
• 90151-40-9 4-amino-3-methoxybenzaldehyde 
• 23145-67-7 N-(4-Nitro-3-methoxy-benzyl)-anthranilsaeure 
• 578-46-1 5-methyl-2-nitroaniline 
• 39538-68-6 2-methoxy-4-methylaniline 
• 4532-33-6 1-methoxy-3-methylcarbazole 
• 808114-08-1 (2-methoxy-4-methylphenyl)phenylamine 
• 28096-94-8 (E)-4,4'-diamino-3,3'-dimethoxystilbene 
• 35387-92-9 methyl 4-iodo-3-methoxybenzoate 
• 41608-64-4 methyl 3-methoxy-4-aminobenzoate 
• 5081-37-8 methyl 3-methoxy-4-nitrobenzoate 
• 208399-31-9 N,N',N''-(nitrilotri-2,1-ethanediyl)tris(2,2'-dihydroxy-4-biphenylcarboxamide) 
• 208399-30-8 N,N',N''-(nitrilotri-2,1-ethanediyl)tris(2,2'-dimethoxy-4-biphenylcarboxamide) 
• 723-97-7 murrayanine 

Relevant articles and documents

NEW COMPOUND HAVING FGFR INHIBITORY ACTIVITY AND PREPARATION AND APPLICATION THEREOF

The present invention relates to a new compound having an FGFR inhibitory activity and preparation and application thereof. In particular, the compound according to the present invention has a structure as shown in formula I, wherein each group and substituent are as defined in the description. Also disclosed in the present invention are a preparation method for the compound and a use thereof in preparation of a drug for treating and/or preventing a tumor-related disease and/or an FGFR-related disease.

A tandem reduction-oxidation protocol for the conversion of 1-keto-1,2,3,4-tetrahydrocarbazoles to carbazoles via tosylhydrazones through microwave assistance: Efficient synthesis of glycozoline, clausenalene, glycozolicine, and deoxycarbazomycin B and the total synthesis of murrayafoline A

A novel and efficient methodology for the synthesis of carbazoles from 1-keto-1,2,3,4-tetrahydrocarbazoles via the corresponding tosylsulfonhydrazones by a one-pot tandem reduction-oxidation protocol using a combination of NaBH4 and Pd-C on MgSO4·7H2O, a solid support, under microwave is developed. The reaction is successfully extended toward the synthesis of several naturally occurring carbazole alkaloids, namely 3-methylcarbazole, glycozoline, clausenalene, glycozolicine, murrayafoline A, and deoxycarbazomycin B, a carbazole derivative that is known to have a promising antimicrobial activity.

COMPOSITIONS CONTAINING, METHODS INVOLVING, AND USES OF NON-NATURAL AMINO ACIDS AND POLYPEPTIDES

Disclosed herein are non-natural amino acids and polypeptides that include at least one non-natural amino acid, and methods for making such non-natural amino acids and polypeptides. The non-natural amino acids, by themselves or as a part of a polypeptide, can include a wide range of possible functionalities, but typical have at least one aromatic amine group. Also disclosed herein are non-natural amino acid polypeptides that are further modified post-translationally, methods for effecting such modifications, and methods for purifying such polypeptides. Typically, the modified non-natural amino acid polypeptides include at least one alkylated amine group. Further disclosed are methods for using such non-natural amino acid polypeptides and modified non-natural amino acid polypeptides, including therapeutic, diagnostic, and other biotechnology uses.