221177-50-0

Basic information

• Product Name: 2-[5-chloro-2-(trityloamino)phenyl]-4-cyclopropyl-1,1,1-trifluorobut-3-yn-2-ol
• Synonyms: 2-[5-chloro-2-(trityloamino)phenyl]-4-cyclopropyl-1,1,1-trifluorobut-3-yn-2-ol
• CAS NO: 221177-50-0
• Molecular Weight: 532.005
• Mol File: 221177-50-0.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 2-[5-chloro-2-(trityloamino)phenyl]-4-cyclopropyl-1,1,1-trifluorobut-3-yn-2-ol(CAS DataBase Reference)
• NIST Chemistry Reference: 2-[5-chloro-2-(trityloamino)phenyl]-4-cyclopropyl-1,1,1-trifluorobut-3-yn-2-ol(221177-50-0)
• EPA Substance Registry System: 2-[5-chloro-2-(trityloamino)phenyl]-4-cyclopropyl-1,1,1-trifluorobut-3-yn-2-ol(221177-50-0)

Safety Data

• Hazardous Substances Data: 221177-50-0(Hazardous Substances Data)

Upstream product

• 6746-94-7 Cyclopropylacetylene 
• 209460-09-3 1-[5-chloro-2-(tritylamino)phenyl]-2,2,2-trifluoroethan-1-one 

Downstream Products

• 221177-51-1 trans-6-Amino-3-chloro-α-(2-cyclopropylethenyl)-α-(trifluoromethyl)benzyl alcohol 
• 168834-43-3 6-amino-3-chloro-α-cyclopropylethynyl-α-(trifluoromethyl)benzyl alcohol 
• 209414-27-7 (2S)-2-(2-amino-5-chlorophenyl)-4-cyclopropyl-1,1,1-trifluorobut-3-yn-2-ol 

Relevant articles and documents

NHC-Copper(I) Halide-Catalyzed Direct Alkynylation of Trifluoromethyl Ketones on Water

An efficient and easily scalable NHC-copper(I) halide-catalyzed addition of terminal alkynes to 1,1,1-trifluoromethyl ketones, carried out on water for the first time, is reported. A series of addition reactions were performed with as little as 0.1-2.0?mo

5,5-disubstituted-1,5-dihydro-4,1-benzoxazepin-2 (3H)-ones useful as HIV reverse transcriptase inhibitors

The present invention relates to benzoxazepinones of formula I: STR1 or stereoisomeric forms or mixtures, or pharmaceutically acceptable salt forms thereof, which are useful as inhibitors of HIV reverse transcriptase, and to pharmaceutical compositions and diagnostic kits comprising the same and methods of using the same for treating viral infection or as an assay standard or reagent.