22126-16-5 Usage
Uses
Used in Pharmaceutical Industry:
4,6-Dimethylpyrimidine-2-carbonitrile is used as a key intermediate in the synthesis of various drugs and bioactive molecules. Its unique chemical structure allows for the creation of a wide range of pharmaceutical compounds with diverse therapeutic applications.
Used in Anti-Cancer Research:
4,6-Dimethylpyrimidine-2-carbonitrile is used as a potential anti-cancer agent due to its inhibitory effects on specific enzyme targets. It has been studied for its ability to interfere with the growth and progression of cancer cells, making it a valuable tool in the development of novel cancer therapies.
Used in Medicinal Chemistry:
4,6-Dimethylpyrimidine-2-carbonitrile is used as a versatile building block in the synthesis of other organic compounds. Its chemical properties and reactivity make it an important component in the development of new chemical entities with potential applications in the field of medicinal chemistry.
Check Digit Verification of cas no
The CAS Registry Mumber 22126-16-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,2,1,2 and 6 respectively; the second part has 2 digits, 1 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 22126-16:
(7*2)+(6*2)+(5*1)+(4*2)+(3*6)+(2*1)+(1*6)=65
65 % 10 = 5
So 22126-16-5 is a valid CAS Registry Number.
InChI:InChI=1/C7H7N3/c1-5-3-6(2)10-7(4-8)9-5/h3H,1-2H3
22126-16-5Relevant academic research and scientific papers
Chiral Crystals of an Achiral Molecule Exhibit Plastic Bending and a Crystal-to-Crystal Phase Transition
Maahs, Adam C.,Ignacio, Melissa G.,Ghazzali, Mohamed,Soldatov, Dmitriy V.,Preuss, Kathryn E.
, p. 1390 - 1395 (2017/03/11)
The achiral molecule 2-cyano-4,6-dimethylpyrimidine (Me2pmCN) meets simple criteria that predict a supramolecular arrangement capable of exhibiting plastic bending. Indeed, crystals grown by sublimation bend readily without breaking under manua
3-Quinuclidinol as a nucleophilic catalyst for the cyanation of 2-chloropyrimidines
Kim, Hong-Yong,Shieh, Wen-Chung,Prashad, Mahavir
, p. 5055 - 5057 (2015/01/09)
3-Quinuclidinol serves as an effective nucleophilic catalyst for the preparation of 2-cyanopyrimidines by cyanation of 2-chloropyrimidines with potassium cyanide in good yields.
Synthesis of Cyano-Substituted Heterocycles by Means of Tetraethylammonium Cyanide
Hermann, Klaus,Simchen, Gerhard
, p. 333 - 341 (2007/10/02)
Chloropyrimidines 2, 3 and Chlorquinazolines 9, 10, after conversion into trimethylammonio derivatives 4, 5, 11, 12, react with tetraethylammonium cyanide 1a under very mild conditions to give pyrimidine carbonitriles 6, 7 and quinazoline carbonitriles 13, 14.Direct synthesis of quinoxaline carbonitriles 19 is possible by reaction of chloroquinoxalines 15, 18 with 1a.
