221374-48-7

Basic information

• Product Name: N-{(S)-1-[(2R,3S)-2-((4S,5R)-3,4-Dimethyl-2-oxo-5-phenyl-imidazolidine-1-carbonyl)-3-methyl-aziridine-1-carbonyl]-3-methyl-butyl}-acetamide
• Synonyms: N-{(S)-1-[(2R,3S)-2-((4S,5R)-3,4-Dimethyl-2-oxo-5-phenyl-imidazolidine-1-carbonyl)-3-methyl-aziridine-1-carbonyl]-3-methyl-butyl}-acetamide
• CAS NO: 221374-48-7
• Molecular Weight: 428.531
• Mol File: 221374-48-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-{(S)-1-[(2R,3S)-2-((4S,5R)-3,4-Dimethyl-2-oxo-5-phenyl-imidazolidine-1-carbonyl)-3-methyl-aziridine-1-carbonyl]-3-methyl-butyl}-acetamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-{(S)-1-[(2R,3S)-2-((4S,5R)-3,4-Dimethyl-2-oxo-5-phenyl-imidazolidine-1-carbonyl)-3-methyl-aziridine-1-carbonyl]-3-methyl-butyl}-acetamide(221374-48-7)
• EPA Substance Registry System: N-{(S)-1-[(2R,3S)-2-((4S,5R)-3,4-Dimethyl-2-oxo-5-phenyl-imidazolidine-1-carbonyl)-3-methyl-aziridine-1-carbonyl]-3-methyl-butyl}-acetamide(221374-48-7)

Safety Data

• Hazardous Substances Data: 221374-48-7(Hazardous Substances Data)

Upstream product

• 1188-21-2 N-Ac-Leu 
• 176791-95-0 (4R,5S)-1,5-Dimethyl-3-((2R,3S)-3-methyl-aziridine-2-carbonyl)-4-phenyl-imidazolidin-2-one 

Downstream Products

• 221374-50-1 (S)-2-Acetylamino-4-methyl-pentanoic acid [(1R,2S)-1-((4S,5R)-3,4-dimethyl-2-oxo-5-phenyl-imidazolidine-1-carbonyl)-2-hydroxy-propyl]-amide 
• 221374-49-8 N-{(S)-1-[(4R,5S)-4-((4S,5R)-3,4-Dimethyl-2-oxo-5-phenyl-imidazolidine-1-carbonyl)-5-methyl-4,5-dihydro-oxazol-2-yl]-3-methyl-butyl}-acetamide 

Relevant articles and documents

Synthesis of optically pure threonine-containing dipeptides by regio- and stereo-controlled ring expansion of aziridine-2-imide derivatives

The regio- and stereo-selective ring expansion of chiral N-(α-amino acyl)aziridine-2-imides to oxazolines and subsequent ring opening to optically pure threonine-containing dipeptides with the desired stereochemistry is described.