2216-35-5Relevant academic research and scientific papers
Copper nanoparticle-catalyzed cross-coupling of alkyl halides with Grignard reagents
Kim, Ju Hyun,Chung, Young Keun
supporting information, p. 11101 - 11103 (2013/11/19)
A cross-coupling reaction between alkyl bromides and chlorides and various Grignard reagents was carried out in the presence of commercially available copper or copper oxide nanoparticles as a catalyst and an alkyne additive. The catalytic system shows high activity, a broad scope, and good functional group tolerance.
Highly efficient oxidative bromination of alkanes with the HBr-H 2O2 system in the presence of catalyst
Li, Yujin,Ju, Jie,Jia, Jianhong,Sheng, Weijian,Han, Liang,Gao, Jianrong
experimental part, p. 2428 - 2432 (2011/10/03)
Various cycloalkanes and straight-chain alkanes were efficiently brominated with an aqueous HBr-H2O2 system. This oxidative brominating process was promoted by catalysis and irradiation with light. The cycloalkanes were converted to the corresponding bromo-cycloalkanes in moderate yields and the straight-chain alkanes produced dominantly secondary bromides. This simple but effective bromination method of alkanes is characterized by high atom efficiency, inexpensive reagents and the absence of organic waste, which make it a good alternative to the existing method for Ci£H activation through bromination. A simple, effective, environmentally friendly method was researched for bromination of alkanes in good yield with HBr as the origin of bromine.
The Fast and Selective Reduction of Organic Halides by Lithium Hydrotri-s-butylborate
KIM, Sunggak,YI, Kyu Yang
, p. 789 - 790 (2007/10/02)
Lithium hydrotri-s-butylborate is shown to be a powerful reducing agent in its reducing abilities toward organic halides and discriminates structurally different organic halides due to the bulkiness of the reagent.Essentially complete utilization of the hydride of the reagent for the reduction of organic halides is also of synthetic significance.
DESIGN AND REACTIVITY OF ORGANIC FUNCTIONAL GROUPS: THE HIGHLY CRYSTALLINE 2-ALKOXY N,N'-DIPHENYL-1,3,2-DIAZAPHOSPHOLANES AND THEIR FACILE CONVERSION INTO ALKYL HALIDES
Hanessian, Stephen,Leblanc, Yves,Lavallee, Pierre
, p. 4411 - 4414 (2007/10/02)
Functionalization of alcohols as 2-alkoxy N,N'-diphenyl-1,3,2-diazaphospholanes affords highly crystalline derivatives useful for characterization purposes.These tervalent phosphorus derivatives undergo facile and mild conversion into the corresponding alkyl halides with inversion of configuration.
