2224-37-5

Basic information

• Product Name: 1-nitropentan-2-ol
• Synonyms: 1-nitropentan-2-ol
• CAS NO: 2224-37-5
• Molecular Formula: C₅H₁₁NO₃
• Molecular Weight: 0
• Mol File: 2224-37-5.mol
• Article Data: 31

Chemical Properties

• Boiling Point: 270.66°C (rough estimate)
• Flash Point: 99.1°C
• Appearance: /
• Density: 1.0847
• Vapor Pressure: 0.0181mmHg at 25°C
• Refractive Index: 1.4493
• CAS DataBase Reference: 1-nitropentan-2-ol(CAS DataBase Reference)
• NIST Chemistry Reference: 1-nitropentan-2-ol(2224-37-5)
• EPA Substance Registry System: 1-nitropentan-2-ol(2224-37-5)

Safety Data

• Hazardous Substances Data: 2224-37-5(Hazardous Substances Data)

Usage

Appearance

Colorless to yellow liquid

Odor

Slightly sweet, floral

Functional groups

Nitro group, hydroxyl group

Attached to

Pentane chain

Uses

Intermediate in synthesis of pharmaceuticals and agricultural chemicals, solvent in organic reactions, production of perfumes and flavors

Toxicity

Mildly toxic

Health effects

May cause irritation to skin, eyes, and respiratory system upon exposure

InChI:InChI=1/C5H11NO3/c1-2-3-5(7)4-6(8)9/h5,7H,2-4H2,1H3

Upstream product

• 75-52-5 nitromethane 
• 123-72-8 butyraldehyde 
• 109-67-1 1-penten 
• 66022-60-4 1-nitropent-1-ene 

Downstream Products

• 3156-72-7 (1E)-1-nitropent-1-ene 
• 5343-35-1 1-amino-2-hydroxy-pentane 
• 628-05-7 1-nitropentane 
• 214679-10-4 (1S,2R,1'R)-(-)-N-<2-(1'-tert-butoxycarbonylaminomethylbutoxy)-1-methyl-2-phenylethyl>formamide 
• 214678-95-2 (1S,2R,1'R)-(-)-N-<1-methyl-2-(1'-nitromethylbutoxy)-2-phenylethyl>formamide 
• 214679-14-8 (2R)-(-)-1-tert-butoxycarbonylaminopentan-2-ol 
• 206068-37-3 (R)-2-((R)-2-Oxo-4-phenyl-oxazolidin-3-yl)-pentanoic acid 
• 251464-53-6 (R)-3-((R)-1-Aminomethyl-butyl)-4-phenyl-oxazolidin-2-one 
• 189350-19-4 (R)-3-((R)-1-Nitromethyl-butyl)-4-phenyl-oxazolidin-2-one 
• 2013-12-9 D-norvaline 
• 66022-60-4 1-nitropent-1-ene 

Relevant articles and documents

Tetrabutyldideazaporphyrin

McMurry coupling of a dibutylpyrrole diacrylaldehyde afforded an unstable tetrabutyldideazaporphyrin. Although this porphyrin analogue was highly unstable, proton NMR spectroscopy demonstrated that it retained a high degree of diatropic character.

Waste-to-useful: A biowaste-derived heterogeneous catalyst for a green and sustainable Henry reaction

Owing to the depletion of resources coupled with increasing waste generation, the conversion of waste biomass to value-added materials has gained interest. Here, we report for the first time the application of Musa acuminata (banana) peel ash (MAPA) as a heterogeneous catalyst for C-C bond formation via a Henry reaction under solvent-free conditions at ambient temperature. The catalyst was well characterized using different analytical techniques like FT-IR, SEM, TEM-EDS, XRD, XRF, XPS, BET and TGA, along with basicity determination by a Hammett indicator test and titration method. An excellent yield of nitroalcohol was obtained within 15-30 minutes. No dehydrated product was observed. The catalyst used in these studies has the advantage of being a waste material and is hence low-cost, easily prepared, recyclable and environmentally friendly. In addition, the use of a biogenic renewable catalyst, its atom economy, and room temperature and solvent-free reaction conditions and the avoidance of column chromatography make the protocol highly significant from green and sustainable chemistry perspectives.

2-OXO-1,3-OXAZOLIDINYL IMIDAZOTHIADIAZOLE DERIVATIVES

The present invention relates to 2-oxo-1,3-oxazolidinyl imidazothiadiazole derivatives, processes for preparing them, pharmaceutical compositions containing them and their use as pharmaceuticals.