222420-33-9

Basic information

• Product Name: Propanoic acid, 3-[[2-(aminosulfonyl)phenyl]amino]-3-oxo-, ethyl ester
• CAS NO: 222420-33-9
• Molecular Formula: C11H14N2O5S
• Molecular Weight: 286.309
• Mol File: 222420-33-9.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: Propanoic acid, 3-[[2-(aminosulfonyl)phenyl]amino]-3-oxo-, ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Propanoic acid, 3-[[2-(aminosulfonyl)phenyl]amino]-3-oxo-, ethyl ester(222420-33-9)
• EPA Substance Registry System: Propanoic acid, 3-[[2-(aminosulfonyl)phenyl]amino]-3-oxo-, ethyl ester(222420-33-9)

Safety Data

• Hazardous Substances Data: 222420-33-9(Hazardous Substances Data)

Upstream product

• 3306-62-5 2-AMINOBENZENESULFONAMIDE 
• 36239-09-5 ethyl chlorocarbonylacetate 
• 105-53-3 diethyl malonate 
• 62-53-3 aniline 
• 50881-48-6 N-chlorosulfonyl-N'-phenyl-urea 
• 13338-00-6 2H-1,2,4-benzothiadiazin-3(4H)-one 1,1-dioxide 

Downstream Products

• 1071518-15-4 (1R,2S,7R,8S)-5-(1,1-dioxo-1,4-dihydro-1λ6-benzo[1,2,4]thiadiazin-3-yl)-3-(4-fluorobenzyl)-6-hydroxy-3-azatricyclo[6.2.1.02,7]undec-5-en-4-one 
• 1071521-41-9 (1S,2R,3S,4R)-3-[[2-(1,1-dioxo-1,4-dihydro-1λ6-benzo[1,2,4]thiadiazin-3-yl)-acetyl]-(4-fluorobenzyl)amino]bicyclo[2.2.1]heptane-2-carboxylic acid ethyl ester 
• 303776-89-8 3-(1,1-dioxido-4H-1,2,4-benzothiadiazin-3-yl)-4-hydroxy-1-(3-methylbutyl)-2(1H)-quinolinone 
• 686263-53-6 1-benzyl-3-(1,1-dioxido-4H-1,2,4-benzothiadiazin-3-yl)-4-hydroxy-1,8-naphthyridin-2(1H)-one 
• 53971-22-5 (1,1-dioxo-1,4-dihydro-1λ⁶-benzo-[1,2,4]-thiadiazin-3-yl)acetic acid ethyl ester 
• 53971-22-5 ethyl 1,1-dioxo-2H-benzo-1,2,4-thiadiazinyl-3-acettae 

Relevant articles and documents

Recyclization of 2-imino-2H-1-benzopyrans under the influence of nucleophilic reagents. 2. Reaction of 2-iminocoumarin-3-carboxamides with o-aminobenzenesulfonamide

2-Iminocoumarin-3-carboxamides recyclized into 3-(1,1-dioxo-2H-benzo-1,2,4-thiadiazinyl-3)coumarins under the influence of o-aminobenzenesulfonamide. An alternative method of synthesis is discussed. Proposed mechanisms for the recyclization are discussed.

5,6-DIHYDRO-1H-PYRIDIN-2-ONE COMPOUNDS

The invention is directed to 5,6-dihydro-lH-pyridin-2-one compounds and pharmaceutical compositions containing such compounds that are useful in treating infections by hepatitis C virus.

Inhibitors of HCV NS5B polymerase: Synthesis and structure-activity relationships of N-1-benzyl and N-1-[3-methylbutyl]-4-hydroxy-1,8-naphthyridon-3-yl benzothiadiazine analogs containing substituents on the aromatic ring

A series of non-nucleoside HCV NS5B polymerase inhibitors based on the N-1-benzyl or N-1-[3-methylbutyl]-4-hydroxy-1,8-naphthyridon-3-yl benzothiadiazine core substituted in the D-ring aromatic moiety have been prepared and evaluated. Aromatic substituents extending from position 7 of the D-ring exhibited excellent potency against both genotypes 1a and 1b.