22276-64-8

Basic information

• Product Name: Benzenamine, 2-(3,4-dihydro-6,7-dimethoxy-1-isoquinolinyl)-
• CAS NO: 22276-64-8
• Molecular Formula: C17H18N2O2
• Molecular Weight: 282.342
• Mol File: 22276-64-8.mol
• Article Data: 10

Chemical Properties

• CAS DataBase Reference: Benzenamine, 2-(3,4-dihydro-6,7-dimethoxy-1-isoquinolinyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenamine, 2-(3,4-dihydro-6,7-dimethoxy-1-isoquinolinyl)-(22276-64-8)
• EPA Substance Registry System: Benzenamine, 2-(3,4-dihydro-6,7-dimethoxy-1-isoquinolinyl)-(22276-64-8)

Safety Data

• Hazardous Substances Data: 22276-64-8(Hazardous Substances Data)

Upstream product

• 120-14-9 3,4-dimethoxy-benzaldehyde 
• 552-16-9 ortho-nitrobenzoic acid 
• 4230-93-7 3,4-dimethoxynitrostyrene 
• 118-92-3 anthranilic acid 
• 120-20-7 2-(3,4-dimethoxyphenyl)-ethylamine 
• 60888-85-9 6,7-dimethoxy-1-<(ortho-nitro)phenyl>-3,4-dihydroisoquinoline 
• 610-14-0 2-nitrobenzyl chloride 
• 19007-49-9 N-<(3,4-Dimethoxyphenyl)ethyl>-2-nitrobenzamide 

Downstream Products

• 246851-57-0 N-[2-(6,7-dimethoxy-3,4-dihydro-isoquinolin-1-yl)-phenyl]-4-methyl-benzenesulfonamide 
• 19006-93-0 1-(2-aminophenyl)-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline 
• 10172-51-7 6,7-dimethoxy-1-phenyl-3,4-dihydroisoquinoline 

Relevant articles and documents

Synthesis of Aminoalkyl-Functionalized 4-Arylquinolines from 2-(3,4-Dihydroisoquinolin-1-yl)anilines via the Friedl?nder Reaction

A new approach for the efficient and convenient synthesis of novel aminoalkyl-functionalized 4-arylquinolines via the Friedl?nder reaction of differently substituted 2-(3,4-dihydroisoquinolin-1-yl)anilines with various α-methylene ketones in acetic acid w

Rhodium(III) complexes with isoquinoline derivatives as potential anticancer agents:: In vitro and in vivo activity studies

Two rhodium complexes Rh1 and Rh2 with isoquinoline derivatives were synthesized and characterized. Both complexes displayed strong anticancer activity against various cancer cells and low cytotoxicity against non-cancer cells. These complexes triggered a

Unprecedented SnCl2-mediated cyclization of nitro arenes via N-N bond formation

A mild, efficient, one-pot protocol for the cyclization of nitro-aryl substrates using SnCl2 has been described. The mechanistic course of the reaction suggests the involvement of a hydroxylamine intermediate leading to an intramolecular cyclization via N-N bond formation. The versatility of the methodology has been demonstrated by using two nitro-aryl substrates derived from dihydroisoquinolines and dihydro-β-carbolines. The intramolecular cyclization led to the formation of indazoles in high yields and purities.