222845-31-0

Basic information

• Product Name: (S)-1-(4-iodobutan-2-yl)-4-methylbenzene
• Synonyms: (S)-1-(4-iodobutan-2-yl)-4-methylbenzene
• CAS NO: 222845-31-0
• Molecular Weight: 274.145
• Mol File: 222845-31-0.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (S)-1-(4-iodobutan-2-yl)-4-methylbenzene(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-1-(4-iodobutan-2-yl)-4-methylbenzene(222845-31-0)
• EPA Substance Registry System: (S)-1-(4-iodobutan-2-yl)-4-methylbenzene(222845-31-0)

Safety Data

• Hazardous Substances Data: 222845-31-0(Hazardous Substances Data)

Upstream product

• 1504-75-2 3-(4-methylphenyl)acrylaldehyde 
• 151765-65-0 (S)-3-(4-methylphenyl)butanal 
• 1461-10-5 (S)-3-(4-methylphenyl)-1-butanol 
• 593288-68-7 (S)-3-(4-methylphenyl)butyl 4-methyl-1-benzenesulfonate 
• 130633-06-6 (E)-3-(4-methylphenyl)-but-2-en-1-ol 

Downstream Products

• 3649-81-8 (S)-curcumene 
• 1786-15-8 (S,E)-nuciferol 

Relevant articles and documents

Catalytic enantioselective β-alkylation of α,β-unsaturated aldehydes by combination of transition-metal- and aminocatalysis: Total synthesis of bisabolane sesquiterpenes

Branching out! The first co-catalytic enantioselective (up to 98:2 e.r.) β-alkylation of α,β-unsaturated aldehydes by combination of simple chiral amine and copper catalysts provides β-branched aldehydes in a one-pot protocol (see scheme). The methodology was applied to the short total syntheses of bisabolane sesquiterpenes (S)-(+)-curcumene, (E)-(S)-(+)-3- dehydrocurcumene and (S)-(+)-tumerone.