22312-62-5

Basic information

• Product Name: 2-AMINO-N-M-TOLYL-BENZAMIDE
• Synonyms: m-Benzotoluidide,2-amino- (7CI,8CI); 2-Amino-N-(m-tolyl)benzamide; N-(3-Methylphenyl)2-aminobenzamide
• CAS NO: 22312-62-5
• Molecular Formula: C₁₄H₁₄N₂O
• Molecular Weight: 226.28
• Mol File: 22312-62-5.mol
• Article Data: 16

Chemical Properties

• Boiling Point: 324.1°C at 760 mmHg
• Flash Point: 149.8°C
• Appearance: /
• Density: 1.21g/cm³
• Vapor Pressure: 0.000251mmHg at 25°C
• Refractive Index: 1.671
• CAS DataBase Reference: 2-AMINO-N-M-TOLYL-BENZAMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-AMINO-N-M-TOLYL-BENZAMIDE(22312-62-5)
• EPA Substance Registry System: 2-AMINO-N-M-TOLYL-BENZAMIDE(22312-62-5)

Safety Data

• Hazardous Substances Data: 22312-62-5(Hazardous Substances Data)

Usage

Molar mass

226.28 g/mol

Contains

amino group and a methyl tolyl group

Uses

Building block in organic synthesis and pharmaceutical research

Potential applications

Precursor or intermediate in the production of various organic compounds and pharmaceuticals
Further research needed to explore potential uses and properties.

InChI:InChI=1/C14H14N2O/c1-10-5-4-6-11(9-10)16-14(17)12-7-2-3-8-13(12)15/h2-9H,15H2,1H3,(H,16,17)

Upstream product

• 118-48-9 isatoic anhydride 
• 108-44-1 1-amino-3-methylbenzene 
• 118-92-3 anthranilic acid 
• 91-56-5 indole-2,3-dione 
• 610-14-0 2-nitrobenzyl chloride 
• 552-16-9 ortho-nitrobenzoic acid 
• 5344-90-1 2-Aminobenzyl alcohol 
• 625-95-6 3-Iodotoluene 
• 28144-70-9 anthranilic acid amide 
• 21563-73-5 2-aminobenzoyl chloride 
• 50623-64-8 N-(3-methylphenyl)-2-nitrobenzamide 

Downstream Products

• 497066-79-2 (2-m-tolylcarbamoyl-phenylamino)-acetic acid 
• 183269-70-7 2-[2(R)-Amino-3-mercaptopropylamino]-N-(3-methylphenyl)-benzamide trifluoroacetate 
• 37856-15-8 2-phenyl-3-(m-tolyl)quinazolin-4(3H)-one 
• 22288-99-9 2-methyl-3-(m-tolyl)quinazolin-4(3H)-one 
• 94064-25-2 3-(3-methylphenyl)-4(3H)-quinazolinone 
• 35833-87-5 1-methyl-3-(m-tolyl)-2,3-dihydroquinazolin-4(1H)-one 
• 35833-80-8 2-(methylamino)-N-(m-tolyl)benzamide 
• 143424-24-2 2-[Acetyl-(2,4-dimethoxy-benzyl)-amino]-N-m-tolyl-benzamide 
• 143424-29-7 2-[Acetyl-(3,4-dimethoxy-benzyl)-amino]-N-m-tolyl-benzamide 
• 139602-66-7 2-(2,4-Dimethoxy-benzylamino)-N-m-tolyl-benzamide 
• 139602-71-4 2-(3,4-Dimethoxy-benzylamino)-N-m-tolyl-benzamide 
• 143424-14-0 2-{[1-(2,4-Dimethoxy-phenyl)-meth-(E)-ylidene]-amino}-N-m-tolyl-benzamide 
• 143424-19-5 2-{[1-(3,4-Dimethoxy-phenyl)-meth-(E)-ylidene]-amino}-N-m-tolyl-benzamide 
• 143424-10-6 2-{[1-(4-Methoxy-phenyl)-meth-(E)-ylidene]-amino}-N-m-tolyl-benzamide 

Relevant articles and documents

N,N-Dimethylformamide as Carbon Synthons for the Synthesis ofN-Heterocycles: Pyrrolo/Indolo[1,2-a]quinoxalines and Quinazolin-4-ones

N,N-dimethylformamide (DMF) as synthetic precursors contributing especially the methyl, acyl, and amino groups has played a significant role in heterocycle syntheses and functionalization. In this protocol, a wide range of pyrrolo/indolo[1,2-a]quinoxalines and quinazolin-4-ones were obtained in moderate to good yields by using elemental iodine without any metal or peroxides. We considered thatN-methyl andN-acyl of DMF participate and complete the reaction separately through different mechanisms, which displayed potential still to be explored of DMF.

Synthesis and biological evaluation of novel benodanil-heterocyclic carboxamide hybrids as a potential succinate dehydrogenase inhibitors

In order to discover new antifungal agents, twenty novel benodanil-heterocyclic carboxamide hybrids were designed, synthesized, and characterized by 1H NMR and HRMS. In vitro, their antifungal activities against four phytopathogenic fungi were

Palladium-Catalyzed Oxidative Three-Component Coupling of Anthranilamides with Isocyanides and Arylboronic Acids: Access to 2,3-Disubstituted Quinazolinones

A novel palladium-catalyzed oxidative three-component coupling of easily accessible N-substituted anthranilamides with isocyanides and arylboronic acids is achieved. This protocol offers an alternative approach toward 2,3-disubstituted quinazolinones with a wide substrate scope and good functional group tolerance.