22317-01-7

Usage

Uses

Used in Pharmaceutical and Agrochemical Industries:
1,3-Dimethyl-piperazine is used as a building block for the synthesis of various pharmaceuticals and agrochemicals, contributing to the development of new drugs and pesticides.
Used in Corrosion Inhibition:
1,3-Dimethyl-piperazine is employed as a corrosion inhibitor, protecting materials from degradation in various industrial applications.
Used in Polymer and Surfactant Production:
1,3-DIMETHYL-PIPERAZINE is utilized as an intermediate in the production of polymers and surfactants, enhancing the properties and performance of these materials.
Used in Carbon Capture and Storage Applications:
1,3-Dimethyl-piperazine is investigated for its potential use as a solvent in carbon capture and storage due to its ability to absorb carbon dioxide, offering a solution for reducing greenhouse gas emissions.

Upstream product

• 114649-85-3 1-carbethoxy-2,4-dimethylpiperazine 
• 23936-11-0 3-methylpiperazin-2-one 
• 109-81-9 N-methyl-ethane-1,2-diamine 
• 78-98-8 2-oxopropanal 
• 29906-47-6 1-benzyl-2-methylpiperazin-3-one 
• 29906-54-5 1-benzyl-2-methylpiperazine 
• 109055-55-2 1-benzyl-2,4-dimethylpiperazine 

Downstream Products

• 114649-87-5 Cyclohexyl-(2,4-dimethyl-piperazin-1-yl)-methanone 
• 114649-86-4 1-(N,N-dimethylcarbamoyl)-2,4-dimethylpiperazine 
• 1251462-68-6 C₃₅H₃₅FN₆O₄S 
• 69628-30-4 5,11-Dihydro-11-[(2,4-dimethyl-1-piperazinyl)acetyl]-6H-pyrido-[2,3-b][1,4]benzodiazepin-6-one-hydrochloride 

Relevant academic research and scientific papers

Biocatalytic Access to Piperazines from Diamines and Dicarbonyls

Given the widespread importance of piperazines as building blocks for the production of pharmaceuticals, an efficient and selective synthesis is highly desirable. Here we show the direct synthesis of piperazines from 1,2-dicarbonyl and 1,2-diamine substrates using the R-selective imine reductase from Myxococcus stipitatus as biocatalyst. Various N- and C-substituted piperazines with high activity and excellent enantioselectivity were obtained under mild reaction conditions reaching up to 8.1 g per liter.

Studies in Potential Filaricides: Part 20 - Synthesis of 1,4-Disubstituted Piperazines as Diethylcarbamazine Analogs

A series of substituted 2,4-dimethylpiperazines (10-15), 1-benzyl-2-methylpiperazines (16-19), 1-substituted 3-methylpiperazines (20-25,27) and 1,4-disubstituted piperazines (28-34) have been synthesized starting from 1-benzyl-2-methylpiperazine (9) and 1

C-alkylpiperazines. XII. Synthesis and diuretic activity of compounds structurally related to clopamide

The synthesis and diuretic activity were reported of a series of N1-(4-chloro-3-sulfamoylbenzamide)-N4-alkylpiperazines, 2-methyl- and cis-2,6-dimethyl substituted, structurally related to clopamide, as well as of two N4-alkyl-N1-(4-chloro-3-sulfamoylbenz