29906-47-6

Basic information

• Product Name: Piperazinone, 3-methyl-4-(phenylmethyl)-
• CAS NO: 29906-47-6
• Molecular Formula: C12H16N2O
• Molecular Weight: 204.272
• Mol File: 29906-47-6.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Piperazinone, 3-methyl-4-(phenylmethyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Piperazinone, 3-methyl-4-(phenylmethyl)-(29906-47-6)
• EPA Substance Registry System: Piperazinone, 3-methyl-4-(phenylmethyl)-(29906-47-6)

Safety Data

• Hazardous Substances Data: 29906-47-6(Hazardous Substances Data)

Upstream product

• 3891-07-4 N-(2-Hydroxyethyl)phthalimide 
• 64892-53-1 N-benzylalanine ethyl ester 
• 60930-36-1 ethyl (RS)-2-(benzylideneamino)propanoate 
• 23936-11-0 3-methylpiperazin-2-one 
• 100-44-7 benzyl chloride 

Downstream Products

• 1416958-91-2 (S)-3-allyl-1-benzoyl-4-benzyl-3-methylpiperazin-2-one 
• 1416958-90-1 allyl 4-benzoyl-1-benzyl-2-methyl-3-oxopiperazine-2-carboxylate 
• 22317-01-7 1,3-dimethyl-piperazine 
• 92699-31-5 4-benzyl-3-methyl-piperazine-1-carboxylic acid ethyl ester 
• 114649-89-7 (4-Benzyl-3-methyl-piperazin-1-yl)-cyclohexyl-methanone 
• 114649-91-1 4-Benzyl-3-methyl-piperazine-1-carboxylic acid diethylamide 
• 114649-90-0 4-Benzyl-3-methyl-piperazine-1-carboxylic acid dimethylamide 
• 114649-87-5 Cyclohexyl-(2,4-dimethyl-piperazin-1-yl)-methanone 
• 109055-55-2 1-benzyl-2,4-dimethylpiperazine 
• 114649-85-3 1-carbethoxy-2,4-dimethylpiperazine 
• 114649-86-4 1-(N,N-dimethylcarbamoyl)-2,4-dimethylpiperazine 
• 114649-88-6 1,2-dimethyl-4-(N,N-dimethylcarbamoyl) piperazine 
• 114649-92-2 3-Methyl-piperazine-1-carboxylic acid dimethylamide 
• 114649-94-4 3,4-dimethyl-piperazine-1-carboxylic acid ethyl ester 

Relevant articles and documents

Enantioselective synthesis of α-secondary and α-tertiary piperazin-2- Ones and piperazines by catalytic asymmetric allylic alkylation

The asymmetric palladium-catalyzed decarboxylative allylic alkylation of differentially N-protected piperazin-2- ones allows the synthesis of a variety of highly enantioenriched tertiary piperazine-2-ones. Deprotection and reduction affords the corresponding tertiary piperazines, which can be employed for the synthesis of medicinally important analogues. The introduction of these chiral tertiary piperazines resulted in imatinib analogues which exhibited comparable antiproliferative activity to that of their corresponding imatinib counterparts.