2234-74-4

Basic information

• Product Name: CIS -7,10,13,16,19-DOCOSA- PENTAENOIC ACID
• Synonyms: (7E,10E,13E,16E,19E)-docosa-7,10,13,16,19-pentaenoic acid
• CAS NO: 2234-74-4
• Molecular Formula: C₂₂H₃₄O₂
• Molecular Weight: 330.5042
• Mol File: 2234-74-4.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 442.2°C at 760 mmHg
• Flash Point: 338.9°C
• Appearance: /
• Density: 0.932g/cm³
• Vapor Pressure: 4.69E-09mmHg at 25°C
• Refractive Index: 1.509
• CAS DataBase Reference: CIS -7,10,13,16,19-DOCOSA- PENTAENOIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: CIS -7,10,13,16,19-DOCOSA- PENTAENOIC ACID(2234-74-4)
• EPA Substance Registry System: CIS -7,10,13,16,19-DOCOSA- PENTAENOIC ACID(2234-74-4)

Safety Data

• Hazardous Substances Data: 2234-74-4(Hazardous Substances Data)

Usage

InChI:InChI=1/C22H34O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-22(23)24/h3-4,6-7,9-10,12-13,15-16H,2,5,8,11,14,17-21H2,1H3,(H,23,24)

Upstream product

• 875288-80-5 methyl (2E,7Z,10Z,13Z,16Z,19Z)-docosa-2,7,10,13,16,19-hexaenoate 
• 10417-94-4 all cis-5,8,11,14,17-eicosapentaenoic acid 
• 119818-40-5 (7Z,10Z,13Z,16Z,19Z)-ethyl docosa-7,10,13,16,19-pentaenoate 
• 534-03-2 serinol 
• 66211-46-9 (R)-3-amino-1,2-propanediol 
• 141-43-5 ethanolamine 
• 616-29-5 1,3-Diamino-2-hydroxypropane 
• 61278-21-5 (S)-3-Amino-1,2-propanediol 
• 375387-66-9 (5Z,8Z,11Z,14Z,17Z)-eicosa-5,8,11,14,17-pentaenal 
• 86227-47-6 eicosapentaenoic acid ethyl ester 
• 181213-52-5 ((5Z,8Z,11Z,14Z,17Z)-2-Icosa-5,8,11,14,17-pentaenyl)-malonic acid diethyl ester 
• 181213-47-8 EPA bromide 
• 164221-12-9 (5Z,8Z,11Z,14Z,17Z)-icosa-5,8,11,14,17-pentaen-1-ol 
• 2734-47-6 (5Z,8Z,11Z,14Z,17Z)-5,8,11,14,17-icosapentaenoic acid methyl ester 

Downstream Products

• 351317-23-2 (7Z,10Z,13Z,16Z,19Z)-N-(2-hydroxyethyl)docosa-7,10,13,16,19-pentaenamide 
• 887752-12-7 17-hydroxydocosa-7Z,10Z,13Z,15E,19Z-pentaenoic acid 
• 887752-13-8 7,17-dihydroxydocosa-8E,10Z,13Z,15E,19Z-pentaenoic acid 
• 960593-70-8 docosapentaenoyl chloride 
• 1288971-25-4 C₂₈H₃₉NO₂ 
• 1288970-85-3 C₂₈H₄₀N₂O 
• 1288971-58-3 C₂₆H₄₃NO₂ 
• 1048011-98-8 C₂₈H₄₄O₄ 

Relevant articles and documents

A Convenient Protocol for the Synthesis of Fatty Acid Amides

Several classes of biologically occurring fatty acid amides have been reported from mammalian and plant sources. Many amides conjugated with fatty acids of mammalian origin exhibit specific activation of individual receptors. Their potential as pharmacological tools or as lead compounds towards the development of novel therapeutics is of great interest. Hence, access to such amides by a practical, high-yielding and scalable protocol without affecting the geometry or position of sensitive functionalities is needed. A protocol that meets all these requirements involves activation of the corresponding acid with carbonyl diimidazole (CDI) followed by reaction with the desired amine or its hydrochloride. More than fifty compounds have been prepared in generally high yields.

One-pot synthesis of polyunsaturated fatty acid amides with anti-proliferative properties

A one-pot environmentally friendly transamidation of ω-3 fatty acid ethyl esters to amides and mono- or diacylglycerols was investigated via the use of a polymer-supported lipase. The method was used to synthesize a library of fatty acid monoglyceryl esters and amides. These new derivatives were found to have potent growth inhibition effects against A549 lung cancer cells.

PROCESS FOR PREPARING AND PURIFYING FATTY ACIDS

There is provided a process for purifying a fatty acid, which process comprises reacting a fatty acid with a lithium salt in a first solution and under conditions to allow formation of a precipitate of a lithium salt of the fatty acid; isolating the precipitate; dissolving the precipitate in a second solution followed by separation of the organic and aqueous layers so formed; and evaporating the organic layer to isolate the purified fatty acid. There is also provided a process for increasing the length of a fatty acid, and the use of a lithium salt to purify a fatty acid.