22375-05-9

Basic information

• Product Name: 2-Hydroxy-6-methyl-4-(phenylmethoxy)benzoic acid methyl ester
• Synonyms: 2-Hydroxy-6-methyl-4-(phenylmethoxy)benzoic acid methyl ester
• CAS NO: 22375-05-9
• Molecular Formula: C₁₆H₁₆O₄
• Molecular Weight: 272.3
• Mol File: 22375-05-9.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-Hydroxy-6-methyl-4-(phenylmethoxy)benzoic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Hydroxy-6-methyl-4-(phenylmethoxy)benzoic acid methyl ester(22375-05-9)
• EPA Substance Registry System: 2-Hydroxy-6-methyl-4-(phenylmethoxy)benzoic acid methyl ester(22375-05-9)

Safety Data

• Hazardous Substances Data: 22375-05-9(Hazardous Substances Data)

Upstream product

• 3187-58-4 methyl orsellinate 
• 100-39-0 benzyl bromide 
• 100-44-7 benzyl chloride 
• 620-05-3 iodomethylbenzene 
• 67-56-1 methanol 
• 480-64-8 orsellinic acid 
• 940289-70-3 7-hydroxy-2,2,5-trimethyl-4H-benzo[d][1,3]dioxin-4-one 

Downstream Products

• 22375-06-0 4-benzyloxy-2-methoxy-6-methylbenzoic acid 
• 60556-48-1 (4-Benzyloxy-2-methoxy-6-methyl-phenyl)-(2,4,6-tris-benzyloxy-phenyl)-methanone 
• 60556-49-2 (4-Hydroxy-2-methoxy-6-methyl-phenyl)-(2,4,6-trihydroxy-phenyl)-methanone 
• 96682-21-2 4-benzyloxy-3,5-dichloro-2-methoxy-6-methylbenzoic acid 
• 96682-20-1 methyl-4-benzyloxy-3,5-dichloro-2-methoxy-6-methylbenzoate 
• 96682-22-3 2,4-dichloro-3-hydroxy-5-methoxy-toluene 
• 4101-80-8 dichloroisoeverninic acid 
• 141861-72-5 6-benzyloxy-2,4-dichloro-1,3-dihydroxy-8-methyl-9H-xanthen-9-one 
• 236751-74-9 2-iodo-6-methoxycarbonyl-3-(methoxymethoxy)methyl-5-methylphenyl 7-chloro-4-hydroxy-5,8-dimethoxy-2-naphthoate 
• 236751-38-5 methyl 2-methoxymethoxy-6-methyl-4-(trifluoromethylsulfonyloxy)benzoate 
• 236751-40-9 1-methyl 4-phenyl 2-methoxymethoxy-6-methylterephthalate 
• 236751-48-7 methyl 2-hydroxy-3-iodo-4-(methoxymethoxy)methyl-6-methylbenzoate 
• 236751-42-1 methyl 2-methoxymethoxy-4-(methoxymethoxy)methyl-6-methylbenzoate 
• 1007851-31-1 methyl 4-hydroxymethyl-2-methoxymethoxy-6-methylbenzoate 

Relevant articles and documents

Photolytic Studies on the Generation and Trapping of 6-Oxomethylidenecyclohexa-2,4-diene-1-one Derivatives with Various Nucleophiles

α-Oxoketenes and cyclohexadiene α-oxoketenes are reactive intermediates, particularly the latter due to their high re-aromatization potential. In this communication, we report photolytic studies on the generation of such species from 4-OMe and 4-OMOM protected resorcylate dioxinones and their trapping to give resorcylate esters and amides as well as the formation of adducts with enol-ethers as trapping reagents.

First Total Synthesis of (3 R,4 S)-4-Hydroxylasiodiplodin: A Facile and Stereoselective Approach

A first total synthesis of (3R,4S)-4-hydroxylasiodiplodin is described starting from methyl acetoacetate and a commonly available carbohydrate, d-mannitol, which is regularly used in organic synthesis. The facile and stereoselective approach involves the

SYNTHESES OF 4-HYDROXY-5-IODO-2,3-DIMETHOXY-6-METHYLBENZOIC ACID AND 5-BROMO-4-HYDROXY-2,3-DIMETHOXY-6-METHYLBENZOIC ACID - AROMATIC CONSTITUENTS OF THE CALICHEMICINS

4-Hydroxy-5-iodo-2,3-dimethoxy-6-methylbenzoic acid (1) and 5-bromo-4-hydroxy-2,3-dimethoxy-6-methylbenzoic acid (2) are the polysubstituted aromatic carboxylic acids found in calichemicin antibiotics.The title compounds are synthesized on preparative sca

Improved Synthesis of Dichloroisoeverninic Acid

The Dichlorination of methyl isoeverninate 7a gave the geminal dichloroketone 12 as the major product.The title compound 1 was therefore synthesized via dichlorination of 4-protected methyl orsellinate 5a using the pivaloyloxy-function as a new protecting group in resorcyclic acids chemistry. - Keywords: 3,5-Dichloro-4-hydroxy-2-methoxy-6-methylbenzoic Acid, Dichloroisoeverninic Acid