2243-81-4

Basic information

• Product Name: NAPHTHALENE-1-CARBOXAMIDE
• Synonyms: 1-NAPTHAMIDE;1-NAPHTHALIMIDE;1-NAPHTHAMIDE;A-NAPHTHAMIDE;ALPHA-NAPHTHAMIDE;ALPHA-NAPTHOIC ACID AMIDE;NAPHTHALENE-1-CARBOXAMIDE;1-Naphthalenecarboxamide
• CAS NO: 2243-81-4
• Molecular Formula: C₁₁H₉NO
• Molecular Weight: 171.2
• Product Categories: Aromatic Carboxylic Acids, Amides, Anilides, Anhydrides & Salts
• Mol File: 2243-81-4.mol
• Article Data: 11

Chemical Properties

• Melting Point: 201-204°C
• Boiling Point: 301.18°C (rough estimate)
• Flash Point: 196.6°C
• Appearance: /
• Density: 1.1242 (rough estimate)
• Vapor Pressure: 1.18E-06mmHg at 25°C
• Refractive Index: 1.4900 (estimate)
• Storage Temp.: Sealed in dry,Room Temperature
• Solubility: DMSO (Slightly), Methanol (Slightly, Heated)
• PKA: 16.00±0.30(Predicted)
• BRN: 2044731
• CAS DataBase Reference: NAPHTHALENE-1-CARBOXAMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: NAPHTHALENE-1-CARBOXAMIDE(2243-81-4)
• EPA Substance Registry System: NAPHTHALENE-1-CARBOXAMIDE(2243-81-4)

Safety Data

• Hazard Codes: Xi
• Safety Statements: 22-24/25
• HazardClass: IRRITANT, IRRITANT-HARMFUL
• Hazardous Substances Data: 2243-81-4(Hazardous Substances Data)

Usage

Uses

1-Naphthamide can be used to induce plant rooting.

InChI:InChI=1/C11H9NO/c12-11(13)10-7-3-5-8-4-1-2-6-9(8)10/h1-7H,(H2,12,13)

Upstream product

• 91-20-3 naphthalene 
• 51-79-6 urethane 
• 86-53-3 1-Cyanonaphthalene 
• 118-31-0 (naphth-1-yl)methylamine 
• 13504-46-6 1-naphtylaldehyde oxime 
• 27466-85-9 N-benzyl-1-naphthamide 
• 66-77-3 1-naphthaldehyde 
• 4780-79-4 1-naphthalene methanol 
• 127099-85-8 N-Cyanoguanidine 
• 201230-82-2 carbon monoxide 
• 90-11-9 1-Bromonaphthalene 
• 74-88-4 methyl iodide 

Downstream Products

• 4780-79-4 1-naphthalene methanol 
• 1975-44-6 5-nitro-1-naphthoic acid 
• 1253388-75-8 C₃₉H₂₅NO 
• 40054-08-8 2-(naphthalen-1-yl)-4,5-dihydrooxazole 
• 27466-85-9 N-benzyl-1-naphthamide 
• 3400-33-7 N-methyl-1-naphthalenecarboxamide 
• 642-29-5 1-benzoylnaphthalene 
• 3007-97-4 ethyl 1-naphthoate 
• 20300-10-1 1-naphthalenecarbothioamide 
• 118-31-0 (naphth-1-yl)methylamine 
• 1330785-43-7 ethyl 2-(1-naphthamido)-2-(4-methoxyphenylamino)acetate 
• 613-46-7 2-naphthalenecarbonitrile 
• 66-77-3 1-naphthaldehyde 
• 13026-12-5 3-(1-naphthyl)propenoic acid 

Relevant articles and documents

Direct conversion of aromatic aldehydes into benzamides via oxidation with potassium permanganate in liquid ammonia

Oxidation of aromatic aldehydes by KMnO4 in liquid ammonia gives amides directly. The reaction proceeds satisfactorily when the aldehydes are activated by electron-withdrawing substituents on the ring.

Benzamide synthesis by direct electrophilic aromatic substitution with cyanoguanidine

Cyanoguanidine is an inexpensive commodity chemical and it is found to be a useful reagent for the direct Friedel-Crafts carboxamidation of arenes. The reaction works best in an excess of Bronsted superacid, an observation suggesting the involvement of a superelectrophilic intermediate. Theoretical calculations indicate that the most stable diprotonated species involves protonation at the guanidine and cyano nitrogen atoms.

Room-temperature debenzylation of N-benzylcarboxamides by N-bromosuccinimide

A simple and highly efficient method has been developed with which to cleave the N-benzyl group on N-mono- or disubstituted carboxamides using N-bromosuccinimide (NBS) at room temperature. All the 31 substrates examined showed moderate to excellent deprotection yields. Our study also indicated that the debenzylation may involve an oxygen/light initiated free radical mechanism. Georg Thieme Verlag Stuttgart.