22545-14-8

Basic information

• Product Name: 2-(2-ethoxyphenyl)ethanol
• Synonyms: 2-(2-ethoxyphenyl)ethanol;2-ethoxyBenzeneethanol;2-(2-ETHOXYPHENYL)ETHAN-1-OL
• CAS NO: 22545-14-8
• Molecular Formula: C₁₀H₁₄O₂
• Molecular Weight: 166.21696
• Mol File: 22545-14-8.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 261.4°Cat760mmHg
• Flash Point: 106.5°C
• Appearance: /
• Density: 1.037g/cm³
• Vapor Pressure: 0.00588mmHg at 25°C
• Refractive Index: 1.519
• CAS DataBase Reference: 2-(2-ethoxyphenyl)ethanol(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(2-ethoxyphenyl)ethanol(22545-14-8)
• EPA Substance Registry System: 2-(2-ethoxyphenyl)ethanol(22545-14-8)

Safety Data

• Hazardous Substances Data: 22545-14-8(Hazardous Substances Data)

Usage

General Description

2-(2-ethoxyphenyl)ethanol is a chemical compound that belongs to the class of phenyl alcohols. It is a colorless liquid with a faint, floral odor, and is commonly used as a fragrance ingredient in cosmetic and personal care products. It is also used as a solvent in various industrial applications, such as in the production of coatings, paints, and other chemical processes. The compound is also known for its antimicrobial properties, making it an effective ingredient in disinfectant and antiseptic products. Additionally, 2-(2-ethoxyphenyl)ethanol has been studied for its potential use as a drug carrier in pharmaceutical applications due to its ability to enhance the solubility of various drugs.

InChI:InChI=1/C10H14O2/c1-2-12-10-6-4-3-5-9(10)7-8-11/h3-6,11H,2,7-8H2,1H3

Upstream product

• 7768-28-7 2-(2-hydroxyphenyl)ethanol 
• 75-03-6 ethyl iodide 
• 186019-68-1 methyl 2-(ethoxyphenyl)acetate 
• 22446-37-3 methyl (2-hydroxyphenyl)acetate 
• 75-21-8 oxirane 
• 583-19-7 beta-bromophenetole 
• 95-56-7 2-hydroxybromobenzene 
• 271-89-6 1-benzofurane 
• 41842-29-9 2-ethoxyphenylmagnesium bromide 

Downstream Products

• 1434644-00-4 1-ethoxy-2-(2-iodoethyl)benzene 
• 61850-95-1 ethoxyphenethyl bromide 

Relevant articles and documents

Antiproliferative activity and SARs of caffeic acid esters with mono-substituted phenylethanols moiety

A series of CAPE derivatives with mono-substituted phenylethanols moiety were synthesized and evaluated by MTT assay on growth of 4 human cancer cell lines (Hela, DU-145, MCF-7 and ECA-109). The substituent effects on the antiproliferative activity were systematically investigated for the first time. It was found that electron-donating and hydrophobic substituents at 2′-position of phenylethanol moiety could significantly enhance CAPE's antiproliferative activity. 2′-Propoxyl derivative, as a novel caffeic acid ester, exhibited exquisite potency (IC50?=?0.4?±?0.02 & 0.6?±?0.03?μM against Hela and DU-145 respectively).

CARBOXYLIC ACID DERIVATIVE AND SALT THEREOF

The present invention provides a novel carboxylic acid compound, a salt thereof or a hydrate of them useful as an insulin sensitizer, and a medicament comprising the compound as an active ingredient. That is, the present invention provides a carboxylic acid compound represented by the following formula, a salt thereof, an ester thereof or a hydrate of them. Wherein R1 represents a hydrogen atom, hydroxyl group, halogen, carboxyl group, or a C1-6 alkyl group etc., each of which may have one or more substituents; L represents a single bond, or a C1-6 alkylene group, a C2-6 alkenylene group or a C2-6 alkynylene group, each of which may have one or more substituents; M represents a single bond, or a C1-6 alkylene group, a C2-6 alkenylene group or a C2-6 alkynylene group, each of which may have one or more substituents; T represents a single bond, or a C1-3 alkylene group, a C2-3 alkenylene group or a C2-3 alkynylene group, each of which may have one or more substituents; W represents a carboxyl group;- - - represents a single bond etc. ; X represents a single bond, oxygen atom, a group represented by -NRX1CQ1O- (wherein Q1 represents an oxygen atom or sulfur atom; and RX1 represents a hydrogen atom, formyl group, or a C1-6 alkyl group etc., each of which may have one or more substituents), -OCQ1NRX1- (wherein Q1 and RX1 are as defined above), -CQ1NRx1O- (wherein Q1 and RX1 are as def ined above), ONRX1CQ1- (wherein Q1 and RX1 are as defined above), - Q2SO2- (wherein Q2 is an oxygen atom or -NRX10- (wherein RX10 represents a hydrogen atom, formyl group, or a C1-6 alkyl group etc., each of which may have one or more substituents)) or -SO2Q2- (wherein Q2 is as defined above), (wherein, provided that RX2 and RX3, and/or RX4 and RX5 may together form a ring, Q3 and Q4 are the same as or different from each other and each represents an oxygen atom, (O)S(O) or NRX10 (wherein NRX10 is as defined above)); Y represents a 5- to 14-membered aromatic group etc., which may have one or more substituents and one or more hetero atoms; and the ring Z represents a 5-to 14-membered aromatic group which may have 0 to 4 substituents and one or more hetero atoms, and wherein part of the ring may be saturated.