7768-28-7

Basic information

• Product Name: 2-HYDROXYPHENETHYL ALCOHOL
• Synonyms: 2-(2-Hydroxyethyl)phenol;2-(2-Hydroxyphenyl)ethanol;2-(o-Hydroxyphenyl)ethanol;beta-(o-Hydroxyphenyl)ethanol;o-(2-Hydroxyethyl)phenol;o-Hydroxyphenethyl alcohol;Phenethyl alcohol, o-hydroxy-;2-HYDROXYPHENETHYL ALCOHOL
• CAS NO: 7768-28-7
• Molecular Formula: C₈H₁₀O₂
• Molecular Weight: 138.16
• EINECS: 231-863-3
• Product Categories: Alcohols;C7 to C8;Oxygen Compounds;Building Blocks;C7 to C8;Chemical Synthesis;Organic Building Blocks;Oxygen Compounds
• Mol File: 7768-28-7.mol
• Article Data: 19

Chemical Properties

• Boiling Point: 168-169 °C2 mm Hg(lit.)
• Flash Point: >230 °F
• Appearance: Clear yellow to yellow-brownish/Viscous Liquid
• Density: 1.159 g/mL at 25 °C(lit.)
• Vapor Pressure: 1.83E-05mmHg at 25°C
• Refractive Index: n20/D 1.559(lit.)
• Storage Temp.: Sealed in dry,Room Temperature
• Solubility: Chloroform, DMSO (Slightly), Methanol (Slightly)
• Stability: Light Sensitive
• CAS DataBase Reference: 2-HYDROXYPHENETHYL ALCOHOL(CAS DataBase Reference)
• NIST Chemistry Reference: 2-HYDROXYPHENETHYL ALCOHOL(7768-28-7)
• EPA Substance Registry System: 2-HYDROXYPHENETHYL ALCOHOL(7768-28-7)

Safety Data

• Hazard Codes: Xn,Xi
• Statements: 22-41-36/37/38
• Safety Statements: 26-37/39-36
• WGK Germany: 2
• Hazardous Substances Data: 7768-28-7(Hazardous Substances Data)

Usage

Chemical Properties

Clear yellow liquid

Uses

2-Hydroxybenzeneethanol can be used to synthesize cyclic products and organoaluminim oligomers. Inelastic electron tunnelling spectra of 2-hydroxyphenethyl alcohol adsorbed on thin-film aluminium and magnesium oxide has been investigated.

Definition

ChEBI: A phenol that is 2-phenylethanol in which the phenyl ring is substituted at position 2 by a hydroxy group.

General Description

2-Hydroxyphenethyl alcohol reacts with triethyl or trimethyl aluminium to yield cyclic products and organoaluminim oligomers. Inelastic electron tunnelling spectra of 2-hydroxyphenethyl alcohol adsorbed on thin-film aluminium and magnesium oxide has been investigated.

InChI:InChI=1/C8H10O2/c9-6-5-7-3-1-2-4-8(7)10/h1-4,9-10H,5-6H2

Upstream product

• 496-16-2 2.3-dihydrobenzofuran 
• 60-12-8 2-phenylethanol 
• 1091-24-3 1,1-diphenyl-2,3-dihydro-1H-benzo[b]silole 
• 18666-27-8 1-phenyl-2-(diphenylsilyl)ethane 
• 100-42-5 styrene 
• 108-95-2 phenol 
• 103588-71-2 (Z)-β-tert-butyldimethylsilyloxystyrene 
• 122-78-1 phenylacetaldehyde 
• 271-89-6 1-benzofurane 
• 64-17-5 ethanol 
• 553-86-6 benzofuran-2(3H)-one 
• 614-75-5 2-Hydroxyphenylacetic acid 
• 154582-38-4 2-(o-cyanomethyl)phenethyl alcohol 
• 82700-26-3 tert-Butyl-(3,8a-dihydro-benzo[c][1,2]dioxin-3-yloxy)-dimethyl-silane 

Downstream Products

• 22545-14-8 2-(2-ethoxyphenyl)ethanol 
• 71263-04-2 2-[2-(2,4-Dichloro-benzyloxy)-phenyl]-ethanol 
• 61850-95-1 ethoxyphenethyl bromide 
• 909114-13-2 ethyl 2-[2-(2-hydroxy-ethyl)-phenoxy]-2-methyl-propionate 
• 1030829-49-2 2-(2-phenoxyphenyl)ethan-1-ol 

Relevant articles and documents

Boron insertion into alkyl ether bonds via zinc/nickel tandem catalysis

Mild methods to cleave the carbon-oxygen (C?O) bond in alkyl ethers could simplify chemical syntheses through the elaboration of these robust, readily available precursors. Here we report that dibromoboranes react with alkyl ethers in the presence of a nickel catalyst and zinc reductant to insert boron into the C?O bond. Subsequent reactivity can effect oxygen-to-nitrogen substitution or one-carbon homologation of cyclic ethers and more broadly streamline preparation of bioactive compounds. Mechanistic studies reveal a cleavage-then-rebound pathway via zinc/nickel tandem catalysis.

Synthesis of high added value compounds through catalytic oxidation of 2-phenylethanol: A Kinetic study

An effective procedure was developed to produce high-value added phenolic compounds through the conversion of 2-phenylethanol (2-PhEt) by using acid-activated clays KSF for the hydrogen peroxide. Owing to KSF's ability to catalyze a variety of complex oxi

Two new aromatic glycosides, elengiosides A and B, from the flowers of Mimusops elengi

Two new aromatic glycosides, elengiosides A (1) and B (2), were isolated from the methanolic extract of the flowers of Mimusops elengi (Sapotaceae) together with 26 known compounds. Their stereostructures were elucidated based on their spectroscopic properties and chemical evidence. Among the isolates, a phenylethanoid glycoside, undatuside C (14), was found to exhibit hyaluronidase inhibitory activity.