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226-36-8

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226-36-8 Usage

Description

DIBENZ(A,H)ACRIDINE is a heterocyclic aromatic compound characterized by its potent mutagenic and carcinogenic properties. It is one of the azaarenes found in grilled meat and is also identified as a urinary metabolite resulting from inhalation and dermal exposure to polycyclic aromatic hydrocarbons in hot mix asphalt paving workers. DIBENZ(A,H)ACRIDINE is presented in the form of yellow crystals and is insoluble in water.

Uses

Used in Industrial Applications:
DIBENZ(A,H)ACRIDINE is used as a chemical compound in the industry for various purposes, primarily due to its mutagenic and carcinogenic properties. It serves as a marker for exposure to polycyclic aromatic hydrocarbons, which are common in certain occupational settings like hot mix asphalt paving.
Used in Environmental and Occupational Health:
In the field of environmental and occupational health, DIBENZ(A,H)ACRIDINE is utilized as a biomarker to monitor the exposure levels of workers to polycyclic aromatic hydrocarbons. This helps in assessing the potential health risks associated with these hazardous substances and implementing necessary safety measures.
Used in Research and Toxicology:
DIBENZ(A,H)ACRIDINE is employed as a research compound in toxicology and molecular biology. Its mutagenic and carcinogenic properties make it a valuable tool for studying the mechanisms of cancer development and the effects of various chemicals on genetic material.
Used in Analytical Chemistry:
As a component of grilled meat, DIBENZ(A,H)ACRIDINE is used in analytical chemistry to study the formation and presence of azaarenes in food products. This aids in understanding the potential health implications of consuming such compounds and developing methods to reduce their formation during cooking processes.

Reactivity Profile

DIBENZ(A,H)ACRIDINE neutralizes acids in exothermic reactions to form salts plus water. May be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. May generate hydrogen, a flammable gas, in combination with strong reducing agents such as hydrides.

Safety Profile

Confirmed carcinogen with experimental carcinogenic and tumorigenic data. Mutation data reported. When heated to decomposition it emits toxic fumes of NOx. See also ANTHRACENE.

Check Digit Verification of cas no

The CAS Registry Mumber 226-36-8 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 2,2 and 6 respectively; the second part has 2 digits, 3 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 226-36:
(5*2)+(4*2)+(3*6)+(2*3)+(1*6)=48
48 % 10 = 8
So 226-36-8 is a valid CAS Registry Number.
InChI:InChI=1/C21H13N/c1-3-7-17-14(5-1)11-12-20-19(17)13-16-10-9-15-6-2-4-8-18(15)21(16)22-20/h1-13H

226-36-8 Well-known Company Product Price

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  • Cerilliant

  • (ERD-013)  Dibenz(a,h)acridine  vial of 25 mg, analytical standard

  • 226-36-8

  • ERD-013-25MG

  • 657.54CNY

  • Detail

226-36-8SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 20, 2017

Revision Date: Aug 20, 2017

1.Identification

1.1 GHS Product identifier

Product name 7-Azadibenz(a,h)anthracene

1.2 Other means of identification

Product number -
Other names 1,2,5,6-Dibenzacridine

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:226-36-8 SDS

226-36-8Relevant articles and documents

Copper-Catalyzed N,N-Diarylation of Amides for the Construction of 9,10-Dihydroacridine Structure and Applications in the Synthesis of Diverse Nitrogen-Embedded Polyacenes

Tan, Mei-Ling,Tong, Shuo,Hou, Sheng-Kai,You, Jingsong,Wang, Mei-Xiang

, p. 5417 - 5422 (2020/07/08)

We reported herein CuI/DMEDA catalyzed N,N-diarylation reaction of amides with various di(o-bromoaryl)methanes to produce diverse 9,10-dihydroacridine derivatives. The resulting 9,10-dihydroacridine derivatives were oxidized selectively under mild conditions to afford acridine, acridinone, and acridinium derivatives. The copper-catalyzed N,N-diarylation reaction coupled with oxidative aromatization reaction enabled the facile construction of nitrogen atom-embedded tetracenes and pentacenes of different ortho-fused patterns. The luminescence properties, especially the effect of fusion pattern on fluorescence emission of acquired N-polycenes, were also demonstrated.

REGIOSELECTIVE CYCLISATION OF ANIL DERIVATIVES - A SHORT SYNTHESIS OF DIBENZACRIDINES

Kar, Gandhi K.,Karmakar, Arun Ch.,Ray, Jayanta K.

, p. 223 - 224 (2007/10/02)

Dibenzacridines have been synthesized in almost quantitative yields by regioselective thermal cyclisation of anil hydrochlorides followed by dehydrogenation.

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