226067-50-1

Upstream product

• 100-52-7 benzaldehyde 
• 167259-92-9 N-Acetyl-(1S,5R,7R)-10,10-Dimethyl-3-thioxo-2-aza-4-oxatricyclo<5.2.1.0^1,5>decane 

Downstream Products

• 2768-42-5 (R)-3-phenyl-3-hydroxypropionic acid 
• 170108-73-3 phenylmethyl (R)-3-hydroxy-3-phenylpropanoate 
• 54713-14-3 (2S,3S)-3-Phenyl-oxirane-2-carboxylic acid 
• 226067-54-5 (2R,3S)-2-bromo-3-hydroxy-3-phenylpropanoic acid 

Relevant academic research and scientific papers

Asymmetric bromination-aldolization of chiral acetate titanium enolate derived from thioimide. A general approach to the synthesis of enantiopure α-bromo-β-hydroxy carboxylic acids

Chiral acetate titanium enolate derived from thioimide efficiently effects one-step bromination-aldolization with excellent yields and exceptionally high levels of asymmetric induction in aldol additions. General base promoted oxazolidinethione deacylatio

An efficient method for the synthesis of enantiopure cis-α,β-epoxy acids

Enantiopure cis-α,β-epoxy acids were prepared via a modified Darzen's reaction employing the titanium-mediated bromination-aldolization of chiral acetate thioimide enolate.