Asymmetric bromination-aldolization of chiral acetate titanium enolate derived from thioimide. A general approach to the synthesis of enantiopure α-bromo-β-hydroxy carboxylic acids

DOI: 10.1016/S0040-4039(99)00576-6

Source and publish data:

Tetrahedron Letters p. 3577 - 3580 (1999)

Update date:2022-08-16

Topics:

Authors:

Wang, Ying-Chuan

Su, Dah-Wei

Lin, Chen-Men

Tseng, Hsi-Liang

Li, Chi-Lung

Yan, Tu-Hsin

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Article abstract of DOI:10.1016/S0040-4039(99)00576-6

Chiral acetate titanium enolate derived from thioimide efficiently effects one-step bromination-aldolization with excellent yields and exceptionally high levels of asymmetric induction in aldol additions. General base promoted oxazolidinethione deacylatio

Full text of DOI:10.1016/S0040-4039(99)00576-6

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