22609-01-4

Usage

General Description

6-Chloro-3-ethoxycarbonyl-2-methyl-4-phenylquinoline is a chemical compound with the molecular formula C20H17ClNO2. It is a quinoline derivative that contains a chlorine atom, an ethoxycarbonyl group, a methyl group, and a phenyl group. This chemical compound has potential applications in pharmaceutical and medicinal chemistry due to its structural features and properties. It may be used as a building block in the synthesis of biologically active compounds and drugs, and its unique structure may contribute to its pharmacological properties and potential therapeutic effects. Additionally, research into the uses and properties of 6-Chloro-3-ethoxycarbonyl-2-methyl-4-phenylquinoline may provide insights into its potential applications in various fields.

Upstream product

• 141-97-9 ethyl acetoacetate 
• 719-59-5 5-chloro-2-aminobenzophenone 
• 15933-07-0 Ethyl 2-oxobutanoate 
• 1159372-20-9 (2-amino-5-chlorophenyl)(phenyl)methanol 
• 2835-77-0 (2-aminophenyl)(phenyl)methanone 
• 609-15-4 ethyl 2-chloro-3-oxo-butyrate 
• 4341-76-8 Ethyl 2-butynoate 

Downstream Products

• 312758-85-3 C₁₇H₁₂ClNO₂ 

Relevant academic research and scientific papers

Green synthesis of trimetallic oxide nanoparticles and their use as an efficient catalyst for the green synthesis of quinoline and spirooxindoles: Antibacterial, cytotoxicity and anti-colon cancer effects

The three-metallic oxide (Cu/Cr/Ni) nanoparticles were prepared using Echinops persicus plant extract via a simple, biocompatible, cost-effective, and non-toxic procedure, and their catalytic activity was evaluated over the synthesis of biologically activ

Environmentally Friendly Nafion-Mediated Friedl?nder Quinoline Synthesis under Microwave Irradiation: Application to One-Pot Synthesis of Substituted Quinolinyl Chalcones

An efficient and eco-friendly synthetic route for Friedl?nder quinoline synthesis of polysubstituted quinolines is described. This green chemical method starts from various 2-aminobenzophenones and mono- or dicarbonyl synthons and uses reusable Nafion NR50 material as a solid catalyst in ethanol under microwave irradiation. The protocol has a high generality of functional groups and provides the desired quinolines in good to excellent yields. Some structures were confirmed by single-crystal X-ray diffraction analysis.

Magnetic Fe–Cr–Ni oxide alloy nano-belts prepared from the chemical decomposition of a stainless steel screw (a top-down approach): an efficient and cheap catalyst for multicomponent reactions

Abstract: A new, cheap, and accessible method has been used for the preparation of nano-belts from the chemical decomposition (top-down approach) of a cheap stainless steel screw and found as an efficient magnetically recyclable nanocatalyst for the prepa

Flexible Zn-MOF Exhibiting Selective CO2 Adsorption and Efficient Lewis Acidic Catalytic Activity

A two-dimensional, tetragonal porous metal organic framework {[Zn2(TBIB)2(HTCPB)2]·9DMF·19H2O}n (1) has been synthesized under hydrothermal conditions by employing 1,3,5-tri(1H-benzo[d]imidazol-1-yl)b

A mild and efficient Ga(OTF)3-catalysed Friedl?nder reaction for the synthesis of quinolines

– The application of gallium triflate [Ga(OTf)3] for the synthesis of quinolines via the Friedl?nder reaction is described. This mild and straightforward method employed only 1 mol% of Ga(OTf)3 to deliver the quinoline products in excellent yields, demons

Synthesis of Fe3O4?SiO2/isoniazid/Cu(II) magnetic nanocatalyst as a recyclable catalyst for a highly efficient preparation of quinolines in moderate conditions

This paper reports the investigation on an efficient procedure to prepare Fe3O4?SiO2/isoniazid/Cu(II) as a recoverable magnetic nanocatalyst. The prepared nanocatalyst, Fe3O4?SiO2/isoniazid

Synthesis and evaluation of novel triazolyl quinoline derivatives as potential antileishmanial agents

The high potential of quinoline containing natural products and their derivatives in medicinal chemistry led us to discover novel series of 25 compounds for the development of new antileishmanial agents. A series of triazolyl 2-methyl-4-phenylquinoline-3-carboxylate derivatives has been synthesized via click chemistry inspired molecular hybridization approach and evaluated against Leishmania donovani. Most of the screened derivatives exhibited significant in vitro anti-leishmanial activity against promastigote (IC50 ranging from 2.43 to 45.75 μM) and intracellular amastigotes (IC50 ranging from 7.06 to 34.9 μM) than the control, miltefosine (IC50 = 8.4 μM), with less cytotoxicity in comparison to the standard drugs. Overall results revealed that prototype signify a new structural lead for antileishmanial chemotherapy.

ZnCl2 supported on Fe3O4@SiO2 core–shell nanocatalyst for the synthesis of quinolines via Friedl?nder synthesis under solvent-free condition

A magnetic nanocatalyst of Fe3O4@SiO2/ZnCl2 was prepared by supporting ZnCl2 on silica-coated magnetic nanoparticles of Fe3O4. This recoverable catalyst was used for the synthesi

A NbO type Cu(II) metal-organic framework showing efficient catalytic activity in the Friedl?nder and Henry reactions

A three-dimensional NbO type porous metal-organic framework 1 containing both tertiary amine groups and paddle wheel dinuclear Cu2(COO)4 secondary building units as the active centre was synthesized at room temperature. The activated