226415-08-3 Usage
Uses
Used in Nucleic Acid Research:
N6-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-fluoro-2'-deoxy-arabinoadenosine is used as a research tool for studying the structure and function of nucleic acids. The chemical modifications allow for the investigation of how these changes affect the stability, binding, and reactivity of nucleic acid molecules.
Used in Drug Development:
In the pharmaceutical industry, N6-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-fluoro-2'-deoxy-arabinoadenosine is utilized as a starting material or intermediate in the synthesis of new drugs. The unique properties conferred by the chemical modifications can be leveraged to develop pharmaceuticals with specific targets and therapeutic effects, potentially leading to novel treatments for various diseases.
Used in Chemical Synthesis:
N6-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-fluoro-2'-deoxy-arabinoadenosine is also used as a building block in the synthesis of more complex organic molecules. The presence of the benzoyl and dimethoxytrityl groups provides opportunities for further chemical reactions, enabling the creation of a wide range of molecules with diverse applications in various fields.
Check Digit Verification of cas no
The CAS Registry Mumber 226415-08-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,2,6,4,1 and 5 respectively; the second part has 2 digits, 0 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 226415-08:
(8*2)+(7*2)+(6*6)+(5*4)+(4*1)+(3*5)+(2*0)+(1*8)=113
113 % 10 = 3
So 226415-08-3 is a valid CAS Registry Number.
226415-08-3Relevant academic research and scientific papers
A new synthetic approach to the clinically useful, anti-HIV-active nucleoside, 9-(2,3-dideoxy-2-fluoro-β-D-threo-pentofuranosyl)adenine (β- FddA). Introduction of a 2'-β-fluoro substituent via inversion of a readily obtainable 2'-α-fluoro isomer
Siddiqui, Maqbool A.,Driscoll, John S.,Marquez, Victor E.
, p. 1657 - 1660 (2007/10/03)
A convenient route to the anti-HIV active compound, 9-(2,3-dideoxy-2- fluoro-β-D-threo-pentofuranosyl)adenine (1, β-FddA) started with the facile introduction of fluorine at C2' from the α-side of protected 9-(β-D- arabinofuranosyl)adenine (ara-A). Inversion of the stereochemistry at C2' was accomplished via a stable vinyl intermediate (6), which underwent stereoselective reduction of the double bond to give the desired 2'-F-threo isomer with the opposite β-fluoro stereochemistry.
