227018-14-6 Usage
General Description
The chemical compound "(PYRIDIN-2-YLMETHYL)(PYRIDIN-4-YLMETHYL)AMINE" is a heterocyclic amine with two pyridine groups. It is a tertiary amine with the molecular formula C12H14N2, and it is commonly used as a building block in organic synthesis. (PYRIDIN-2-YLMETHYL)(PYRIDIN-4-YLMETHYL)AMINE is known for its reactivity and is often used in the production of pharmaceuticals, agrochemicals, and other fine chemicals. It can also be used as a catalyst or as an intermediate in the synthesis of other complex organic compounds. The presence of two pyridine groups in the molecule makes it suitable for a variety of chemical reactions and makes it valuable in the field of organic chemistry.
Check Digit Verification of cas no
The CAS Registry Mumber 227018-14-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,2,7,0,1 and 8 respectively; the second part has 2 digits, 1 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 227018-14:
(8*2)+(7*2)+(6*7)+(5*0)+(4*1)+(3*8)+(2*1)+(1*4)=106
106 % 10 = 6
So 227018-14-6 is a valid CAS Registry Number.
227018-14-6Relevant articles and documents
Low-Molecular-Weight CXCR4 Ligands with Variable Spacers
Narumi, Tetsuo,Aikawa, Haruo,Tanaka, Tomohiro,Hashimoto, Chie,Ohashi, Nami,Nomura, Wataru,Kobayakawa, Takuya,Takano, Hikaru,Hirota, Yuki,Murakami, Tsutomu,Yamamoto, Naoki,Tamamura, Hirokazu
, p. 118 - 124 (2013/02/26)
Low-molecular-weight CXCR4 ligands based on known lead compounds including the 14-mer peptide T140, the cyclic pentapeptide FC131, peptide mimetics, and dipicolylamine-containing compounds were designed and synthesized. Three types of aromatic spacers, 1,4-phenylenedimethanamine, naphthalene-2,6-diyldimethanamine, and [1,1′-biphenyl]-4,4′-diyldimethanamine, were used to build four pharmacophore groups. As pharmacophore groups, 2-pyridylmethyl and 1-naphthylmethyl are present in all of the compounds, and several aromatic groups and a cationic group from 1-propylguanidine and 1,1,3,3-tetramethyl-2-propylguanidine were also used. Several compounds showed significant CXCR4 binding affinity, and zinc(II) complexation of bis(pyridin-2-ylmethyl)amine moieties resulted in a remarkable increase in CXCR4 binding affinity.
