227018-72-6

Upstream product

• 70-55-3 toluene-4-sulfonamide 
• 210349-18-1 (E)-7-iodo-3-hepten-2-one 
• 1088669-92-4 C₁₄H₁₉NO₃S 
• 227018-65-7 (E)-7-chloro-3-hepten-2-one 
• 98-59-9 p-toluenesulfonyl chloride 
• 67488-67-9 (-)-(S)-[N-(p-tolylsulfony)-2-pyrrolidinyl]acetonitrile 
• 847062-72-0 diethyl (-)-(S)-{[N-(p-tolylsulfonyl)-2-pyrrolidinyl]acetyl}malonate 
• 147-85-3 L-proline 
• 23356-96-9 (S)-1-Pyrrolidin-2-yl-methanol 
• 52682-03-8 (S)(-)-N,O-bis(p-toluenesulphonyl)-2-hydroxymethyl pyrrolidine 
• 67488-68-0 (-)-(S)-[N-(p-tolylsulfonyl)-2-pyrrolidinyl]acetic acid 

Downstream Products

• 847062-79-7 (2R,2'S)-1-methyl-2-[N-(p-tolylsulfonyl)-2-pyrrolidinyl]ethyl 2,3,4-tri-O-acetyl-β-L-fucopyranoside 
• 847062-80-0 (2S,2'R)-1-methyl-2-[N-(p-tolylsulfonyl)-2-pyrrolidinyl]ethyl 2,3,4-tri-O-acetyl-β-L-fucopyranoside 

Relevant academic research and scientific papers

A ruthenium-catalyzed, atom-economical synthesis of nitrogen heterocycles

The Ruthenium catalyzed, atom-economical domino redox isomerization/cyclization of tethered aminopropargyl alcohols is reported. This process displays a broad scope and functional group tolerance. Furthermore, it presents a novel retrosynthetic disconnect

Total synthesis and identification of two diastereoisomers of 1-methyl-2-[N-(p-tolylsulfonyl)-2-pyrrolidinyl]ethyl β-L-fucopyranoside

The reaction of a racemic mixture of (2R,2′S)- and (2S,2′R)-N-(p-tolylsulfonyl)-2-pyrrolidinyl-2-propanol, prepared from (S)-proline, with 2,3,4-tri-O-acetyl-α-l-fucopyranosyl trichloroacetimidate led to both diastereoisomers of the title compound after O-deacetylation.

N-(4-methylbenzenesulfonyl)- pyrrolidines and piperidines by a tandem S(N)2-Michael addition reaction

A tandem S(N)2-Michael addition sequence has been developed for the preparation of N-(4-methylbenzenesulfonyl)- pyrrolidines and piperidines bearing functionalized side chains at C-2.