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5-Pyrimidinecarboxylic acid, 2-chloro-4-[(3-methylphenyl)amino]-, ethyl ester is a complex organic compound with the chemical formula C13H14ClN3O2. It is a derivative of pyrimidinecarboxylic acid, featuring a 2-chloro substitution, a 3-methylphenyl group attached to the 4-position via an amino group, and an ethyl ester group at the 5-position. 5-Pyrimidinecarboxylic acid, 2-chloro-4-[(3-methylphenyl)amino]-, ethyl ester is characterized by its potential pharmaceutical applications, particularly as an intermediate in the synthesis of certain drugs. Its structure provides a foundation for further chemical modifications, which can lead to the development of new therapeutic agents.

227449-09-4

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227449-09-4 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 227449-09-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,2,7,4,4 and 9 respectively; the second part has 2 digits, 0 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 227449-09:
(8*2)+(7*2)+(6*7)+(5*4)+(4*4)+(3*9)+(2*0)+(1*9)=144
144 % 10 = 4
So 227449-09-4 is a valid CAS Registry Number.

227449-09-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name ethyl 2-chloro-4-(3-methylanilino)pyrimidine-5-carboxylate

1.2 Other means of identification

Product number -
Other names 2-chloro-4-[(3-methylphenyl)amino]pyrimidine-5-carboxylic acid ethyl ester

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:227449-09-4 SDS

227449-09-4Relevant academic research and scientific papers

Synthetic studies on novel Syk inhibitors. Part 1: Synthesis and structure-activity relationships of pyrimidine-5-carboxamide derivatives

Hisamichi, Hiroyuki,Naito, Ryo,Toyoshima, Akira,Kawano, Noriyuki,Ichikawa, Atsushi,Orita, Akiko,Orita, Masaya,Hamada, Noritaka,Takeuchi, Makoto,Ohta, Mitsuaki,Tsukamoto, Shin-Ichi

, p. 4936 - 4951 (2007/10/03)

Spleen tyrosine kinase (Syk) is a non-receptor-type tyrosine kinase which mediates diverse responses in haematopoietic cells. Therefore, Syk is an attractive therapeutic target, and in a study of Syk inhibitors as potentially new therapeutic agents, we di

DIAMINOPYRIMIDINECARBOXA MIDE DERIVATIVE

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Page/Page column 18-19, (2008/06/13)

A compound which may be used for the prevention or treatment of respiratory diseases in which STAT 6 is concerned, particularly asthma, chronic obstructive pulmonary disease and the like is provided. A pyrimidine derivative or a salt thereof, which has an arylamino or arylethylamino group which may be substituted with a specified substituent, at the 2-position, amino group substituted with benzyl group or the like, at the 4-position, and carbamoyl group which may be substituted, at the 5-position, is provided.

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