227449-48-1 Usage
Chemical class
Pyrimidine carboxamides
Molecular weight
369.364 g/mol
Structure
Contains a pyrimidine ring, a benzotriazole moiety, and a tolylamine substituent
Biological activities
Potential activities, further studies needed
Pharmaceutical research
May be used as a scaffold for new drug candidates
Pharmacological properties
Require further exploration
Potential applications
Various fields, yet to be determined
Check Digit Verification of cas no
The CAS Registry Mumber 227449-48-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,2,7,4,4 and 9 respectively; the second part has 2 digits, 4 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 227449-48:
(8*2)+(7*2)+(6*7)+(5*4)+(4*4)+(3*9)+(2*4)+(1*8)=151
151 % 10 = 1
So 227449-48-1 is a valid CAS Registry Number.
227449-48-1Relevant academic research and scientific papers
Synthetic studies on novel Syk inhibitors. Part 1: Synthesis and structure-activity relationships of pyrimidine-5-carboxamide derivatives
Hisamichi, Hiroyuki,Naito, Ryo,Toyoshima, Akira,Kawano, Noriyuki,Ichikawa, Atsushi,Orita, Akiko,Orita, Masaya,Hamada, Noritaka,Takeuchi, Makoto,Ohta, Mitsuaki,Tsukamoto, Shin-Ichi
, p. 4936 - 4951 (2007/10/03)
Spleen tyrosine kinase (Syk) is a non-receptor-type tyrosine kinase which mediates diverse responses in haematopoietic cells. Therefore, Syk is an attractive therapeutic target, and in a study of Syk inhibitors as potentially new therapeutic agents, we di
