22751-69-5

Upstream product

• 27845-53-0 (E)-N-cyclohexyl-1-phenylmethanimine 
• 2211-66-7 N-phenyl(methylidene)cyclohexanamine 
• 67-64-1 acetone 
• 1759-68-8 N-benzoylcyclohexylamine 
• 100-52-7 benzaldehyde 
• 108-91-8 cyclohexylamine 

Relevant academic research and scientific papers

Reductive coupling of aldimines mediated with samarium catalyzed by Cp2TiCl2

Reductive coupling of aldimines into vicinal diamines mediated with samarium catalyzed by Cp2TiCl2 proceeds in refluxing THF with good yields.

Direct reductive coupling of secondary amides: Chemoselective formation of vicinal diamines and vicinal amino alcohols

We report the first one-pot reductive homocoupling reaction of secondary amides and cross-coupling reaction of secondary amides with ketones to give secondary vicinal diamines and amino alcohols. This method relies on the direct generation of α-amino carb

Zn-mediated catalytic photoreduction of aldimines. One-pot synthesis and separation of meso and d,l C2 symmetrical diamines

A new one-pot method for the synthesis and selective separation of 1,2-diamines is reported. The methodology, which involves the photoreduction of imines using catalytic amounts of zinc as a photosensitizer, allows the direct preparation and separation of meso and d,l compounds on a multigram scale.

Photoreductive coupling of aldimines. Synthesis of C2 symmetrical diamines

The photoreductive coupling of pyridine-, arene- and alkynecarboxaldimines is a very convenient procedure for the preparation of vicinal diamines in good to excellent yields. The usual trend gave an excess of meso diamine, which enhances the usefulness of

Reductive coupling of aromatic aldehydes and imines by the low valent titanium species generated in the reaction of TiCl4 with Et3N

Aromatic aldehydes and imines are converted to the corresponding diols and diamines using the low valent titanium species generated by the reaction of TiCl4 with triethylamine.

Samarium diiodide/nickel diiodide an efficient system for homo and heterocoupling reactions of imines

Samarium diiodide in the presence of a catalytic amount of nickel diiodide mediates a very fast dimerization of imines into vicinal diamines and the mixed coupling of imines and ketones to give β-amino alcohols.

Organic reaction in water. Part 1. A convenient method for reduction of imines using zinc powder

Reduction of imines was performed with zinc powder in 5% aqNaOH solution without any organic solvents under mild conditions, and the corresponding amines were obtained in good yields.

A Route to Vicinal Diamines from the Samarium(II) Iodide-Mediated Coupling of Aldimines

A new method to construct vicinal diamines from aldimines mediated by the one electron reductant, samarium diiodide is described.The reaction probably involves a ketyl-like radical coupling mechanism.