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3,4-Di-tert-butylthiophene is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

22808-03-3

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22808-03-3 Usage

Synthesis Reference(s)

Tetrahedron Letters, 29, p. 1161, 1988 DOI: 10.1016/S0040-4039(00)86677-0

Check Digit Verification of cas no

The CAS Registry Mumber 22808-03-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,2,8,0 and 8 respectively; the second part has 2 digits, 0 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 22808-03:
(7*2)+(6*2)+(5*8)+(4*0)+(3*8)+(2*0)+(1*3)=93
93 % 10 = 3
So 22808-03-3 is a valid CAS Registry Number.

22808-03-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name 3,4-ditert-butylthiophene

1.2 Other means of identification

Product number -
Other names 3,4-di-tert-butylthiophene

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:22808-03-3 SDS

22808-03-3Relevant academic research and scientific papers

Synthesis of π-conjugated copolymers composed of benzo[2,1,3]thiadiazole and thiophene units bearing various alkyl groups and their application to photovoltaic cells

Lee, Kwang-Hoi,Lee, Ho-Jin,Kuramoto, Kouji,Tanaka, Yohei,Morino, Kazuhide,Sudo, Atsushi,Okauchi, Tatsuo,Tsuge, Akihiko,Endo, Takeshi

, p. 3543 - 3549 (2011)

π-Conjugated polymers, PTOTBT, PTEHTBT, and PTt-BTBT, composed of benzothiadiazole as an electron accepting unit and terthiophene as an electron donating unit in the backbone were prepared. PTOTBT, PTEHTBT, and PTt-BTBT contained side chain groups of n-octyl, 2-ethylhexyl, and t-butyl groups, respectively. Solubility, optical and thermal properties of the polymers showed strong dependences on their side chain groups. PTEHTBT having 2-ethylhexyl groups in the side chain exhibited absorption maximum (Imax) at longer wavelength (565 nm) than PTOTBT (534 nm) and PTt-BTBT (495 nm). PTOTBT showed higher thermal stability than the others. The prepared polymers were employed to polymer solar cells (PSCs) with a configuration of ITO/PEDOT-PSS/polymer: PC61BH/LiF/Al. Power conversion efficiency of the PSC-based on PTEHTBT was 1.32%.

Synthesis, Crystal, and Molecular Structure of 3,4-Di-t-butylthiophen

Brandsma, Lambert,Meijer, Johnny,Verkruijsse, Herman D.,Bokkers, Gysbertus,Duisenberg, Albert J. M.,Kroon, Jan

, p. 922 - 923 (1980)

A successful synthesis of the hitherto unknown 3,4-di-t-butylthiophen and the results of its crystal structure determination are reported.

Synthesis of an octa-tert-butylphthalocyanine: A low-aggregating and photochemically stable photosensitizer

Gobo, Nicholas R. S.,Brocksom, Timothy J.,Zukerman-Schpector, Julio,De Oliveira, Kleber T.

, p. 5028 - 5031 (2013)

The synthesis of a new octa-tert-butylphthalocyanine is described. First, the 4,5-di-tert-butylphthalonitrile building block was synthesized in a six-step approach, in which the last step is a three reaction domino sequence. Then, this phthalonitrile was cyclotetramerized to furnish a new phthalocyanine dye, which presented no aggregation in solution and good photophysical properties. The synthesis of a new octa-tert-butylphthalocyanine is described. First, the 4,5-di-tert-butylphthalonitrile building block was synthesized in a six-step approach, in which the last step is a three reaction domino sequence. Then, this phthalonitrile was cyclotetramerized to furnish a new phthalocyanine dye, which presented no aggregation in solution and good photophysical properties. Copyright

π-Face-selective hetero Diels-Alder reactions of 3,4-di-tert-butylthiophene 1-oxide. An excellent trapping reagent for thioaldehydes and thioketones

Takayama, Jun,Fukuda, Seiko,Sugihara, Yoshiaki,Ishii, Akihiko,Nakayama, Juzo

, p. 5159 - 5162 (2003)

Hetero Diels-Alder reactions of 3,4-di-tert-butylthiophene 1-oxide (1) with thioaldehydes and thioketones take place exclusively, except the reaction with thiobenzophenone, at the syn-π-face of 1 with respect to the S=O bond. The π-face selectivity was ex

The chemistry of the thiosulfinyl group: Preparation, structure, and spectroscopic and chemical properties of cyclic thionosulfites

Nakayama, Juzo,Yoshida, Sanae,Sugihara, Yoshiaki,Sakamoto, Akira

, p. 1451 - 1471 (2005)

Treatment of the tetrahydrothiophene-3,4-diol 5 with 1,1′-thiobis- (1H-benzimidazole) (6) furnished two diastereoisomers of the novel cyclic thionosulfite 4 with different configurations at the pseudo-tetrahedral center of the thiosulfinyl (S=S) group. The configuration of the S=S group of the major diastereoisomer (isolated in 45% yield) was established to be syn to the thiolane ring, as determined by X-ray crystallographic analysis, while that of the minor diastereoisomer (isolated in 10% yield) was anti. 1H-NMR Spectroscopic analysis clarified that the shielding and deshielding zones of the S=S group are similar to those of the well-documented S=O group. Characteristic absorptions of the S=S group in the IR, Roman, and UV/VIS spectra were assigned on the basis of calculations at the B3LYP/6-31G* level. The reactivity of the S=S group toward thermolysis, hydrolysis, and oxidation was examined. The S=S group is more resistant toward oxidation than the divalent sulfide S-atom, but is oxidatively converted to the S=O group.

SYNTHESIS AND REACTIONS OF 3,4-DI-t-BUTYLTHIOPHENE

Nakayama, Juzo,Yamaoka, Shoji,Hoshino, Masamatsu

, p. 1161 - 1164 (1988)

3,4-Di-t-butylthiophene (1) was surprisingly easily synthesized from readily accessible bis(2-t-butyl-2-oxoethyl) sulfide (2).Reactions of 1 with a variety of electrophiles were examined.

So2-extrusion of an 8-thiabicylo[3.2.1]octa-2,6-diene 8,8-dioxide and rearrangement of the resulting cycloheptatriene

Takayama, Jun,Sugihara, Yoshiaki,Nakayama, Juzo

, p. 132 - 137 (2007/10/03)

The reaction of 3,4-di-tert-butylthio-phene 1-oxide (8) with tetrachlorocyclopropene provided 6,7-di-tert-butyl-2,3,4,4-tetrachloro-8-thia- bicylo[3.2.1]-octa-2,6-diene 8-oxide (10), which was oxidized to the corresponding 8,8-dioxide 16 by m-chloroperbenzoic acid. The thermolysis of 16 in refluxing chlorobenzene, xylene, or octane gave 5-tert-butyl-1,2-dichloro-3- [(1,1-dichloro-2,2-dimethyl)propyl]benzene (18) with extrusion of SO2 and 2-tert-butyl-4,5,6-trichloro-9,9-dimethylbicyclo[5.2.0]nona-1,3,5-triene (19) with extrusion of SO2 and HCl in 73-78% combined yields. On the other hand, the thermolysis of 16 in the presence of triethylamine gave 19 as the sole product in 98% yield. A mechanism that involves the initial formation of 4,5-di-tert-butyl-1,2,7,7-tetrachlorocycloheptatriene (17) is proposed to explain the observed products.

Tetracyanoethylene oxide not only oxidizes sulfides to sulfoxides but also reduces sulfoxides to sulfides

Nakayama, Juzo,Tai, Ayako,Iwasa, Sachiko,Furuya, Tomohiro,Sugihara, Yoshiaki

, p. 1395 - 1397 (2007/10/03)

It was found that tetracyanoethylene oxide not only oxidizes sulfides to sulfoxides but also reduces sulfoxides to sulfides with generation of two molecules of carbonyl cyanide. The reaction thus also functions as a new method for generation of carbonyl cyanide.

Reversible disulfur monoxide (S2O)-forming retro-Diels-Alder reaction. Disproportionation of S2O to trithio-ozone (S3) and sulfur dioxide (SO2) and reactivities of S2O and S3

Nakayama, Juzo,Aoki, Satoshi,Takayama, Jun,Sakamoto, Akira,Sugihara, Yoshiaki,Ishii, Akihiko

, p. 9085 - 9093 (2007/10/03)

5,6-Di-tert-buty(-2,3,7-trithiabicyclo[2.2.1]hept-5-ene 7-endo-oxide (4) was prepared by addition of S2Cl2 to 3,4-di-tert- butylthiophene 1-oxide (3) in high yield. The oxidation of 4 with dimethyldioxirane gave a 7:1 isomeric mixture of 5,6-di-tert-butyl-2,3,7- trithiabicyclo[2.2.1]hept-5-ene 2-endo-7-endo-dioxide (5a) and 2-exo-7-endo-dioxide (5b) quantitatively. The thermally labile 5 was shown to undergo a retro-Diels-Alder reaction that produces S2O and 3 in a reversible way. The resulting S2O was trapped by Diels-Alder reactions with dienes to give 3,6-dihydro-1,2-dithiin 1 -oxides in good yields. In the absence of the dienes, S2O disproportionates to SO2 and S3, and the resulting S3 underwent a 1,3-dipolar cycloaddition with 3 on its syn-π-face with respect to the S=O bond to give a trithiolane derivative, whereas in the presence of excess norbornene, it produced the 1,3-dipolar cycloadduct with norbornene in good yield. Thus, the retro-Diels-Alder reaction of 5 functions as an S2O and S3 source. DFT calculations at the B3LYP/6-311+G(3df,2p) level were carried out in order to explain why S2O disproportionates to SO2 and S3 and why S2O acts as a dienophile and not 1,3-dipole, whereas O3 and S3 serve as 1,3-dipoles.

The thiosulfinyl group serves as a stereogenic center and shows diamagnetic anisotropy similar to that of the sulfinyl group

Tanaka, Sanae,Sugihara, Yoshiaki,Sakamoto, Akira,Ishii, Akihiko,Nakayama, Juzo

, p. 9024 - 9025 (2007/10/03)

The pseudotetrahedral geometry of the thiosulfinyl group (>SS) in the thionosulfite which was prepared by treatment of cis-3,4-di-tert-butylthiolane-3,4-diol with 1,1'-thiobisbenzimidazole is stable enough to allow the isolation of two diastereomers. X-ray crystallographic analysis revealed that the configuration of the >S S group of the major diastereomer (45% isolated yield) is syn to the thiolane ring, while that of the minor diastereomer (10% isolated yield) is anti to the thiolane ring. 1H NMR spectrum analysis clarified that the shielding and deshielding zones of the >SS group are similar to those >SS group; Chemical properties of the > 5 S group toward thermolysis, hydrolysis, and oxidation were clarified. The absorptions or bands in the UV/ vis IR and Raman spectra, which originate from the > SSgroup, were assigned on the basis of the B3LYP/ 6-31G* level calculations. Copyright

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