33369-81-2

Basic information

• Product Name: 2,4-Di-tert-butylthiophene
• Synonyms: 2,4-Di-tert-butylthiophene
• CAS NO: 33369-81-2
• Molecular Formula: C₁₂H₂₀S
• Molecular Weight: 0
• Mol File: 33369-81-2.mol
• Article Data: 8

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2,4-Di-tert-butylthiophene(CAS DataBase Reference)
• NIST Chemistry Reference: 2,4-Di-tert-butylthiophene(33369-81-2)
• EPA Substance Registry System: 2,4-Di-tert-butylthiophene(33369-81-2)

Safety Data

• Hazardous Substances Data: 33369-81-2(Hazardous Substances Data)

Upstream product

• 14630-42-3 (3,3-dimethyl-1-butynyl)trimethylsilane 
• 128788-04-5 2,3-di-t-butylthiophene 
• 75-97-8 3,3-dimethyl-butan-2-one 
• 52743-66-5 2,5-di(1,1-dimethylethyl)-1,4-dithiin 
• 51678-62-7 2,6-di(1,1-dimethylethyl)-1,4-dithiin 
• 52196-65-3 1,1'-thiobis(3,3-dimethylbutan-2-one) 
• 211372-54-2 2,4-Di-tert-butyl-tetrahydro-thiophene-2,4-diol 
• 154702-59-7 3,5-di-tert-butyl-2-trichloromethylthiophene 
• 22808-03-3 3,4-di-tert-butylthiophene 
• 917-92-0 3,3-Dimethylbut-1-yne 
• 1689-77-6 2,5-di-tert-butylthiophene 
• 188290-36-0 thiophene 
• 507-20-0 tertiary butyl chloride 
• 67-64-1 acetone 

Downstream Products

• 120159-42-4 3-(3,5-Di-tert-butyl-thiophen-2-yl)-5-phenyl-4,5-dihydro-isoxazole 

Relevant articles and documents

Rhodium-Catalyzed Isomerization and Alkyne Exchange Reactions of 1,4-Dithiins via the 1,2-Ethenedithiolato Rhodium Complex

Rhodium-catalyzed isomerization and alkyne exchange reactions of 1,4-dithiines occurred by cleavage of two C-S bonds. The 2,5- and 2,6-disubstituted 1,4-dithiins underwent isomerization reactions in toluene at 110 °C, providing equilibrium mixtures of isomers. At 150 °C, the reaction of 1,4-dithiins and dimethyl acetylenedicarboxylate gave unsymmetric 2,3-di(methoxycarbonyl)-1,4-dithiins and 2,3-di(methoxycarbonyl)thiophenes, the latter of which were formed by desulfurization of the 1,4-dithiins. A related reaction of the alkyne and a 1,2-dithiete gave a 2,3-di(methoxycarbonyl)thiophene. These reactions are considered to involve 1,2-ethenedithiolato rhodium intermediates.

SYNTHESIS AND ELECTROPHILIC TRICHLOROMETHYLATION OF 2,4-DIALKYLTHIOPHENES. SOME TRANSFORMATIONS OF 2,4-DI-tert-BUTYL-5-(TRICHLOROMETHYL)THIOPHENE

The disproportionation products of the C-protonation of 5-tert-butyl-2-methyl- and 2-ethylthiophene first give 4-tert-butyl-2-methyl- and 2-ethylthiophene. We studied the electrophilic trichloromethylation of a series of 2,4-dialkyl thiophenes and showed that the reaction goes smoothly only for the most sterically hindered 2,4-di-tert-butyl-thiophene. We studied the reaction of 2,4-di-tert-butyl-5-(trichloromethyl)thiophene with some O- and N-nucleophiles.

The first synthesis and properties of 2,3-di-t-butylthiophene. Reaction of 3,4-di-t-butyl-1,2-dithiete with dimethyl acetylenedicarboxylate

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