22812-25-5Relevant academic research and scientific papers
Copper (II) chloride: A regioselective catalyst for oxidative aromatization of pyrazoline, isoxazoline and 3-methyl flavanones
Lokhande, Pradeep D.,Dalvi, Bhakti A.,Humne, Vivek T,Nawghare, Beena R.,Kareem, Abdul
, p. 1091 - 1097 (2014/09/30)
A new protocol has been reported in which a series of pyrazoline, isoxazoline and 3-methyl flavanone has been conveniently aromatized by using CuCl2.2H2O in DMSO within a short reaction time in excellent yields. The attraction of this new protocol is regioselective aromatization of substrate 3i-j and 5a-e which has been carried out to afford the aromatized product with O-allyl group intact in excellent yield.
Selective O-deallylation of dihydropyrazoles by molecular iodine in the presence of active N-allyl and formyl groups
Humne, Vivek T.,Hasanzadeh, Kamal,Lokhande, Pradeep D.
, p. 585 - 595 (2013/07/27)
Selective O-deallylation of dihydropyrazoles has been achieved by use of iodine (10 mol%) in PEG-400 as ecofriendly solvent. Iodine (10 mol%) in dimethyl sulfoxide at 100 C also afforded O-deallylation with aromatization compatible with highly reactive N-
Synthesis of some new pyrimidines and isoxazolines and their pharmacological activity
Basawaraj, Raga,Hassappa, Ravi,Chillargi, Neelavathi,Noola, Shivanand
experimental part, p. 253 - 256 (2011/12/14)
The condensation of 5-methyl-2-hydroxy acetophenone 1 with different aromatic aldehydes in anhyd ethanol in presence of strong alkali gave 1-(5′-methyl-2′-hydroxy phenyl-1′-yl)-3-substituted arylidene-2-propen-1-ones (2a-d). Compounds (2a-d) underwent cyc
Synthesis of pyrazoline and isoxazoline in triethanolamine medium
Agrawal, Nitin N.,Soni
, p. 2700 - 2701 (2007/10/03)
Reactions of chalcones 1a-u with phenylhydrazine and hydrazine hydrate give pyrazolines 2a-u and with hydroxylamine hydrochloride yield isoxazolines 3a-c in triethanolamine medium. The structures of products are established by melting points, chemical studies and spectral data (IR and 1HNMR).
