30036-27-2

Upstream product

• 29976-82-7 1-(2-hydroxy-5-methylphenyl)-3-phenylpropane-1,3-dione 
• 22219-26-7 2'-hydroxy-5'-methylchalkone dibromide 
• 1450-72-2 5-methyl-2-hydroxyacetophenone 
• 100-52-7 benzaldehyde 
• 1775-98-0 2'-hydroxy-5'-methylchalcone 
• 22812-25-5 4-methyl-2-(5-phenyl-4,5-dihydro-isoxazol-3-yl)-phenol 
• 98-88-4 benzoyl chloride 
• 4010-19-9 1-(2-benzoyloxy-5-methylphenyl)-ethanone 
• 29976-75-8 6-methylflavone 
• 104213-89-0 1-(2-hydroxy-5-methylphenyl)-3-phenylpropynone 

Relevant academic research and scientific papers

Selective O-deallylation of dihydropyrazoles by molecular iodine in the presence of active N-allyl and formyl groups

Selective O-deallylation of dihydropyrazoles has been achieved by use of iodine (10 mol%) in PEG-400 as ecofriendly solvent. Iodine (10 mol%) in dimethyl sulfoxide at 100 C also afforded O-deallylation with aromatization compatible with highly reactive N-

Copper (II) chloride: A regioselective catalyst for oxidative aromatization of pyrazoline, isoxazoline and 3-methyl flavanones

A new protocol has been reported in which a series of pyrazoline, isoxazoline and 3-methyl flavanone has been conveniently aromatized by using CuCl2.2H2O in DMSO within a short reaction time in excellent yields. The attraction of this new protocol is regioselective aromatization of substrate 3i-j and 5a-e which has been carried out to afford the aromatized product with O-allyl group intact in excellent yield.

Synthesis of pyrazole and isoxazole in triethanolamine medium

Reactions of 2′-hydroxy chalcone dibromides 2a-1 with phenyl hydrazine and hydrazine hydrate afford pyrazoles 1a-1 and with hydroxylamine hydrochloride give isoxazoles 5a-f in triethanolamine medium. Similarly reaction of β-diketone 3b-e with phenyl hydra

PYRAZOLES AND ISOXAZOLES DERIVED FROM 2-HYDROXYARYL PHENYLETHYNYL KETONES: SYNTHESIS AND SPECTROPHOTOMETRIC EVALUATION OF THEIR POTENTIAL APPLICABILITY AS SUNSCREENS

Reaction of the acetylenic ketones (1) with hydrazine or hydroxylamine leads to the pyrazoles (2) or the isoxazoles (3), respectively.Spectrophotometric evaluation of the UV-photoprotecting ability as compared to p-aminobenzoic acid (PABA) shows that the predicted effectiveness of 2 and the 3-phenylisoxazoles (3B) is very close to that of PABA, while that of the 5-phenylisoxazoles (3A) is clearly lower.The pyrazoles (2) are more stable than PABA upon UV-irradiation in cyclohexane solution.

Reaction of Hydroxylamine Hydrochloride with 2-Hydroxy-4'-methoxy-5-methyldibenzoylmethane and 4'-Methoxy-6-methylflavone

2-Hydroxy-4'-methoxy-5-methyldibenzoylmethane (1) reacts with hydroxylamine hydrochloride in pyridine to give a mixture of 3-(2-hydroxy-5-methylphenyl)-5-(4-methoxyphenyl)isoxazole (2) and 3-(α-hydroxyamino-4-methoxystyryl)-5-methylbenzisoxazole (3).Simil