22835-30-9Relevant academic research and scientific papers
First example of the cascade acylation/IMDAV/ene reaction sequence, leading to N-arylbenzo[f]isoindole-4-carboxylic acids possessing anti-viral activity
Voronov, Alexander A.,Alekseeva, Kseniia A.,Ryzhkova, Elena A.,Zarubaev, Vladimir V.,Galochkina, Anastasia V.,Zaytsev, Vladimir P.,Majik, Mahesh S.,Tilve, Santosh G.,Gurbanov, Atash V.,Zubkov, Fedor I.
supporting information, p. 1108 - 1111 (2018/03/06)
The reaction between readily accessible N-aryl-3-phenylallylamines and maleic anhydride led to unexpected products – polysubstituted hydrogenated benzo[f]isoindole-4-carboxylic acids. This transformation proceeds through a previously unknown sequence of s
Chiral Br?nsted Acid Catalyzed Enantioselective Phosphonylation of Allylamine via Oxidative Dehydrogenation Coupling
Cheng, Ming-Xing,Ma, Ran-Song,Yang, Qiang,Yang, Shang-Dong
, p. 3262 - 3265 (2016/07/13)
A new strategy for the synthesis of chiral α-amino phosphonates by enantioselective C-H phosphonylation of allylamine with phosphite in the presence of a chiral Br?nsted acid catalyst has been developed. This protocol successfully integrates direct C-H oxidation with asymmetric phosphonylation and exhibits high enantioselectivity.
Solvent-free synthesis, DNA-topoisomerase II activity and molecular docking study of new asymmetrically N,N′-substituted ureas
Andressa, Esteves-Souza,Rodrigues-Santos, Claudio E.,De Nigris Del Cistia, Catarina,Da Silva, Daniel Rosa,Sant'Anna, Carlos Mauricio R.,Echevarria, Aurea
, p. 12882 - 12894 (2013/02/22)
A new series of asymmetrically N,N′-substituted ureas 20-25 was prepared using solvent free conditions, which is an eco-friendly methodology, starting with Schiff bases derived from cinnamaldehyde and p-substituted anilines, which are subsequently submitt
Indium-mediated addition of γ-substituted allylic halides to N-aryl α-imino esters: Diastereoselective production of β,β′- disubstituted α-amino acid derivatives with two contiguous stereocenters
Aslam, Nayyar Ahmad,Rajkumar, Vadla,Reddy, Chennakesava,Yasuda, Makoto,Baba, Akio,Babu, Srinivasarao Arulananda
experimental part, p. 4395 - 4411 (2012/09/10)
Chelation-controlled Barbier-type indium-mediated addition of γ-substituted allylic halides to N-aryl (including N-PMP) α-imino- and N-acylhydrazono esters and highly diastereoselective tailoring of functionalized γ,δ-unsaturated β,β'-disubstituted N-aryl
